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Journal Articles

Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis

Rayanne Pinto Costa, Blaise Simplice Talla Nwotchouang, Junyao Yao, Dipankar Biswas, David Casey, Ruel McKenzie, Frederick Sebastian, Rouzbeh Amini, David A. Steinman, Francis Loth
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. April 2023, 145(4): 041001.
Paper No: BIO-21-1404
DOI: https://doi.org/10.1115/1.4055856
Published Online: December 5, 2022
View Article titled, Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
Click here to open pdf in another window PDF for Impact of Blood Rheology on Transition to Turbulence and Wall Vibration Downstream of a Stenosis
Topics: Blood, Flow (Dynamics), Reynolds number, Rheology, Turbulence, Vibration, Water, Fluids, Pipes, Laser Doppler vibrometers
Proceedings Papers

Numerical Simulation of Pulsatile Flow Inside an End-to-Side Vascular Graft

Francis Loth, Kai Kang, Ming Lei
Proc. ASME. IMECE98, Advances in Bioengineering, 79-80, November 15–20, 1998
Paper No: IMECE1998-0039
DOI: https://doi.org/10.1115/IMECE1998-0039
View Paper titled, Numerical Simulation of Pulsatile Flow Inside an End-to-Side Vascular Graft
Click here to open pdf in another window PDF for Numerical Simulation of Pulsatile Flow Inside an End-to-Side Vascular Graft
Topics: Computer simulation, Pulsatile flow, Flow (Dynamics), Geometry, Shear stress
Proceedings Papers

Hydrodynamic Modeling of Cerebrospinal Fluid Motion Within the Spinal Cavity

M. Atif Yardimci, Francis Loth, Noam Alperin
Proc. ASME. IMECE2000, Advances in Bioengineering, 291-292, November 5–10, 2000
Paper No: IMECE2000-2625
DOI: https://doi.org/10.1115/IMECE2000-2625
View Paper titled, Hydrodynamic Modeling of Cerebrospinal Fluid Motion Within the Spinal Cavity
Click here to open pdf in another window PDF for Hydrodynamic Modeling of Cerebrospinal Fluid Motion Within the Spinal Cavity
Topics: Canals, Cavities, Cerebrospinal fluid, Computer simulation, Flow (Dynamics), Geometry, Modeling, Pressure gradient, Shear stress, Spinal cord
Proceedings Papers

Comparison of Experimental and Numerical Simulations of Flow Within an Arterio-Venous Graft

Paul F. Fischer, Seung Lee, Francis Loth, Hisham S. Bassiouny, Nurullah Arslan
Proc. ASME. IMECE2000, Advances in Bioengineering, 275-276, November 5–10, 2000
Paper No: IMECE2000-2617
DOI: https://doi.org/10.1115/IMECE2000-2617
View Paper titled, Comparison of Experimental and Numerical Simulations of Flow Within an Arterio-Venous Graft
Click here to open pdf in another window PDF for Comparison of Experimental and Numerical Simulations of Flow Within an Arterio-Venous Graft
Topics: Computer simulation, Flow (Dynamics), Turbulence, Bifurcation, Computation, Computational fluid dynamics, Fluid dynamics, Laser Doppler anemometry, Reynolds number
Journal Articles

Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions

Rayanne Pinto Costa, Blaise Simplice Talla Nwotchouang, Junyao Yao, Dipankar Biswas, David Casey, Ruel McKenzie, David A. Steinman, Francis Loth
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. March 2022, 144(3): 031008.
Paper No: BIO-21-1111
DOI: https://doi.org/10.1115/1.4052370
Published Online: October 14, 2021
View Article titled, Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions
Click here to open pdf in another window PDF for Transition to Turbulence Downstream of a Stenosis for Whole Blood and a Newtonian Analog Under Steady Flow Conditions
Topics: Blood, Flow (Dynamics), Fluids, Reynolds number, Turbulence, Viscosity, Water, Rheology, Pipes, Shear rate
Journal Articles

Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I

Alaaddin Ibrahimy, Chi-Wen Christina Huang, Abraham F. Bezuidenhout, Philip A. Allen, Rafeeque A. Bhadelia, Francis Loth
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051003.
Paper No: BIO-20-1201
DOI: https://doi.org/10.1115/1.4049788
Published Online: March 4, 2021
View Article titled, Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I
Click here to open pdf in another window PDF for Association Between Resistance to Cerebrospinal Fluid Flow Near the Foramen Magnum and Cough-Associated Headache in Adult Chiari Malformation Type I
Topics: Cerebrospinal fluid, Computational fluid dynamics, Flow (Dynamics), Canals, Magnetic resonance imaging
Journal Articles

Regional Quantification of Brain Tissue Strain Using Displacement-Encoding With Stimulated Echoes Magnetic Resonance Imaging

Soroush Heidari Pahlavian, John Oshinski, Xiaodong Zhong, Francis Loth, Rouzbeh Amini
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2018, 140(8): 081010.
Paper No: BIO-17-1563
DOI: https://doi.org/10.1115/1.4040227
Published Online: June 15, 2018
View Article titled, Regional Quantification of Brain Tissue Strain Using Displacement-Encoding With Stimulated Echoes Magnetic Resonance Imaging
Click here to open pdf in another window PDF for Regional Quantification of Brain Tissue Strain Using Displacement-Encoding With Stimulated Echoes Magnetic Resonance Imaging
Topics: Biological tissues, Brain, Displacement, Magnetic resonance imaging, Encryption
Journal Articles

Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts

Keyvan Amini Khoiy, Dipankar Biswas, Thomas N. Decker, Kourosh T. Asgarian, Francis Loth, Rouzbeh Amini
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2016, 138(11): 111006.
Paper No: BIO-16-1216
DOI: https://doi.org/10.1115/1.4034621
Published Online: October 21, 2016
View Article titled, Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts
Click here to open pdf in another window PDF for Surface Strains of Porcine Tricuspid Valve Septal Leaflets Measured in Ex Vivo Beating Hearts
Topics: Deformation, Pressure, Valves, Pulmonary artery, Annulus, Pumps, Flow (Dynamics), Errors
Includes: Supplementary data
Journal Articles

Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions

Dipankar Biswas, David M. Casey, Douglas C. Crowder, David A. Steinman, Yang H. Yun, Francis Loth
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. July 2016, 138(7): 071001.
Paper No: BIO-14-1507
DOI: https://doi.org/10.1115/1.4033474
Published Online: June 7, 2016
View Article titled, Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions
Click here to open pdf in another window PDF for Characterization of Transition to Turbulence for Blood in a Straight Pipe Under Steady Flow Conditions
Topics: Blood, Flow (Dynamics), Fluids, Pipes, Viscosity, Rheology, Turbulence
Journal Articles

Characterization of the Discrepancies Between Four-Dimensional Phase-Contrast Magnetic Resonance Imaging and In-Silico Simulations of Cerebrospinal Fluid Dynamics

Soroush Heidari Pahlavian, Alexander C. Bunck, Francis Loth, R. Shane Tubbs, Theresia Yiallourou, Jan Robert Kroeger, Walter Heindel, Bryn A. Martin
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2015, 137(5): 051002.
Paper No: BIO-14-1406
DOI: https://doi.org/10.1115/1.4029699
Published Online: May 1, 2015
View Article titled, Characterization of the Discrepancies Between Four-Dimensional Phase-Contrast Magnetic Resonance Imaging and In-Silico Simulations of Cerebrospinal Fluid Dynamics
Click here to open pdf in another window PDF for Characterization of the Discrepancies Between Four-Dimensional Phase-Contrast Magnetic Resonance Imaging and In-Silico Simulations of Cerebrospinal Fluid Dynamics
Topics: Computational fluid dynamics, Flow (Dynamics), Simulation, Magnetic resonance imaging
Includes: Supplementary data
Proceedings Papers

MR Measurement of Pulse Wave Velocity in the Spinal Canal

Bryn A. Martin, Francis Loth, Wojciech Kalata, John N. Oshinski
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 793-794, June 25–29, 2008
Paper No: SBC2008-193082
DOI: https://doi.org/10.1115/SBC2008-193082
View Paper titled, MR Measurement of Pulse Wave Velocity in the Spinal Canal
Click here to open pdf in another window PDF for MR Measurement of Pulse Wave Velocity in the Spinal Canal
Topics: Canals, Waves, Velocity measurement, Cardiac cycle, Cerebrospinal fluid, Diseases, Pressure, Resolution (Optics)
Journal Articles

Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation

Nicholas Shaffer, Bryn A. Martin, Brandon Rocque, Casey Madura, Oliver Wieben, Bermans J. Iskandar, Stephen Dombrowski, Mark Luciano, John N. Oshinski, Francis Loth
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021012.
Paper No: BIO-13-1402
DOI: https://doi.org/10.1115/1.4026316
Published Online: February 5, 2014
View Article titled, Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation
Click here to open pdf in another window PDF for Cerebrospinal Fluid Flow Impedance is Elevated in Type I Chiari Malformation
Topics: Cerebrospinal fluid, Computational fluid dynamics, Flow (Dynamics), Magnetic resonance imaging, Modeling, Boundary-value problems, Anatomy, Biomechanics, Simulation, Statistical analysis
Proceedings Papers

Relation of Cerebrospinal Fluid Flow Impedance and Cerebellar Herniation in Type I Chiari Malformation

Nicholas Shaffer, Bryn Martin, Brandon Rocque, Casey Madura, Bermans Iskandar, Oliver Wieben, Stephen Dombrowski, Mark Luciano, John Oshinski, Francis Loth
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT46A006, June 26–29, 2013
Paper No: SBC2013-14808
DOI: https://doi.org/10.1115/SBC2013-14808
View Paper titled, Relation of Cerebrospinal Fluid Flow Impedance and Cerebellar Herniation in Type I Chiari Malformation
Click here to open pdf in another window PDF for Relation of Cerebrospinal Fluid Flow Impedance and Cerebellar Herniation in Type I Chiari Malformation
Topics: Cerebrospinal fluid, Flow (Dynamics)
Proceedings Papers

The Influence of Coughing on Cerebrospinal Fluid Pressure in an In Vitro Syringomyelia Model With Spinal Canal Stenosis

Bryn A. Martin, Francis Loth
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 893-894, June 17–21, 2009
Paper No: SBC2009-206784
DOI: https://doi.org/10.1115/SBC2009-206784
View Paper titled, The Influence of Coughing on Cerebrospinal Fluid Pressure in an In Vitro Syringomyelia Model With Spinal Canal Stenosis
Click here to open pdf in another window PDF for The Influence of Coughing on Cerebrospinal Fluid Pressure in an In Vitro Syringomyelia Model With Spinal Canal Stenosis
Topics: Biomechanics, Canals, Cerebrospinal fluid, Pressure
Proceedings Papers

Pathological Biomechanics of Cerebrospinal Fluid Pressure in Syringomyelia: Fluid Structure Interaction of an In Vitro Coaxial Elastic Tube System

Bryn A. Martin, Richard Labuda, Thomas J. Royston, John N. Oshinski, Bermans Iskandar, Francis Loth
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 941-942, June 17–21, 2009
Paper No: SBC2009-204685
DOI: https://doi.org/10.1115/SBC2009-204685
View Paper titled, Pathological Biomechanics of Cerebrospinal Fluid Pressure in Syringomyelia: Fluid Structure Interaction of an In Vitro Coaxial Elastic Tube System
Click here to open pdf in another window PDF for Pathological Biomechanics of Cerebrospinal Fluid Pressure in Syringomyelia: Fluid Structure Interaction of an In Vitro Coaxial Elastic Tube System
Topics: Biomechanics, Cerebrospinal fluid, Fluid structure interaction, Pressure, Spinal cord
Proceedings Papers

Towards Non-Invasive Assessment of the Elastic Properties of the Spinal Aqueduct

Bryn A. Martin, Thomas J. Royston, John N. Oshinski, Francis Loth
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 139-140, June 17–21, 2009
Paper No: SBC2009-206788
DOI: https://doi.org/10.1115/SBC2009-206788
View Paper titled, Towards Non-Invasive Assessment of the Elastic Properties of the Spinal Aqueduct
Click here to open pdf in another window PDF for Towards Non-Invasive Assessment of the Elastic Properties of the Spinal Aqueduct
Topics: Aqueducts, Elasticity, Mechanical properties, Pressure, Waves, Geometry, Wave propagation, Cerebrospinal fluid, Fluids, Phantoms
Proceedings Papers

CFD Challenge: Modeling Blood Flow Dynamics in a Cerebral Aneurysm Using Fluent

Nicholas Shaffer, Francis Loth
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 157-158, June 20–23, 2012
Paper No: SBC2012-80877
DOI: https://doi.org/10.1115/SBC2012-80877
View Paper titled, CFD Challenge: Modeling Blood Flow Dynamics in a Cerebral Aneurysm Using Fluent
Click here to open pdf in another window PDF for CFD Challenge: Modeling Blood Flow Dynamics in a Cerebral Aneurysm Using Fluent
Topics: Aneurysms, Blood flow, Computational fluid dynamics, Dynamics (Mechanics), Modeling, Air flow, Cardiovascular system, Cerebrospinal fluid, Flow (Dynamics), Physiology
Proceedings Papers

CFD Challenge: Experimental Benchmarking Data for the Pressure Drop Across a Cerebral Aneurysm Model

Paul Fahy, Michael Walsh, Francis Loth, Florentina Ene, Patrick Delassus, Liam Morris
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 129-130, June 20–23, 2012
Paper No: SBC2012-80442
DOI: https://doi.org/10.1115/SBC2012-80442
View Paper titled, CFD Challenge: Experimental Benchmarking Data for the Pressure Drop Across a Cerebral Aneurysm Model
Click here to open pdf in another window PDF for CFD Challenge: Experimental Benchmarking Data for the Pressure Drop Across a Cerebral Aneurysm Model
Topics: Aneurysms, Aorta, Biomedical imaging, Biomedicine, Computational fluid dynamics, Diseases, Flow (Dynamics), Physiology, Pressure drop, Testing
Proceedings Papers

Fluid Dynamic Analysis of Upper Airway of an Obstructive Sleep Apnea Patient Pre and Post Surgery

Dipankar Biswas, Francis Loth, Matthew L. Krauza, Rachael J. Pohle-Krauza, Adrian G. Dan, John G. Zografakis
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1203-1204, June 20–23, 2012
Paper No: SBC2012-80726
DOI: https://doi.org/10.1115/SBC2012-80726
View Paper titled, Fluid Dynamic Analysis of Upper Airway of an Obstructive Sleep Apnea Patient Pre and Post Surgery
Click here to open pdf in another window PDF for Fluid Dynamic Analysis of Upper Airway of an Obstructive Sleep Apnea Patient Pre and Post Surgery
Topics: Computational fluid dynamics, Dynamic analysis, Fluids, Sleep, Surgery
Proceedings Papers

Flow System to Detect Transitional Flow Based on Pulsed Doppler Ultrasound Velocity Profiles

Narender Ambati, Dipankar Biswas, Francis Loth, Stanley E. Rittgers, Steven A. Jones
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 967-968, June 20–23, 2012
Paper No: SBC2012-80801
DOI: https://doi.org/10.1115/SBC2012-80801
View Paper titled, Flow System to Detect Transitional Flow Based on Pulsed Doppler Ultrasound Velocity Profiles
Click here to open pdf in another window PDF for Flow System to Detect Transitional Flow Based on Pulsed Doppler Ultrasound Velocity Profiles
Topics: Flow (Dynamics), Ultrasound, Fluids, Reynolds number, Turbulence, Water, Blood, Blood flow, Circuits, Pipes