...Michael S. Sacks; Andrew Drach; Chung-Hao Lee; Amir H. Khalighi; Bruno V. Rego; Will Zhang; Salma Ayoub; Ajit P. Yoganathan; Robert C. Gorman; Joseph H., Gorman, III The mitral valve (MV) is the left atrioventricular heart valve that regulates blood flow between the left atrium and left ventricle...

... atrioventricular orifice is achieved when the anterior and posterior leaflets of the mitral valve press together to form a coaptation zone along the free edge of the leaflets. This coaptation zone is critical to valve competency and is maintained by the support of the mitral annulus, chordae tendinae...

...Muralidhar Padala; Michael S. Sacks; Shasan W. Liou; Kartik Balachandran; Zhaoming He; Ajit P. Yoganathan Interest in developing durable mitral valve repair methods is growing, underscoring the need to better understand the native mitral valve mechanics. In this study, the authors investigate...

... as an indication for annular prostheses design. mitral valve finite element modeling The mitral apparatus is composed of four principal substructures: mitral annulus, leaflets, chordae tendineae, and papillary muscles. The proper action of the mitral complex depends on their normal function...

...Zhaoming He; Bo Gao; Shamik Bhattacharya; Tyler Harrist; Sibi Mathew; Wei Sun Mitral valve edge-to-edge repair (ETER) alters valve mechanics, which may impact efficacy and durability of the repair. The objective of this paper was to quantify stretches in the central region of the anterior leaflet...

...Liang Shi; Zhaoming He Edge-to-edge repair (ETER) is a mitral valve repair technique that restores valvular competence by suturing together the free edges of two leaflets. This repair technique alters mitral valve inflow and thus left ventricle hemodynamics during diastole. Our objective...

...Zhaoming He, Ph.D.; Christopher Jowers Proper leaflet coaptation of the mitral valve is vital for a healthy functioning heart. Chordal tension directly affects leaflet coaptation. The C-shaped transducer used previously to measure chordal tension was too big for tension measurement of multiple...

...Andrea Avanzini Edge-to-edge technique is a surgical procedure for the correction of mitral valve leaflets prolapse by suturing the edge of the prolapsed leaflet to the free edge of the opposing one. Suture presence modifies valve mechanical behavior and orifice flow area in the diastolic phase...