... remodeling. To address this knowledge gap, we propose a predictive mathematical model of pressure-mediated femoral artery remodeling following drug-coated balloon deployment, with account of drug-based modulation of resident vascular cell phenotype and common patient comorbidities, namely, hypertension...

... of induced hypertension and a model of connective tissue disorder that results in Marfan syndrome. The mice have identical genetic backgrounds and, in both cases, the data are consistent with the hypothesis considered. In particular, carotid arteries with strong (normal) vasoactive capacity tend to maintain...

... A computational framework was implemented and validated to better understand the hypertensive artery remodeling in both geometric dimensions and material properties. Integrating the stress-modulated remodeling equations into commercial finite element codes allows a better control and visualization of local...

... matching those of the FE model. Three coupled models were developed, a normal LV under normotensive aortic loading (116/80 mm Hg), a mild hypertension (137/89 mm Hg) model, and a moderate hypertension model (165/100 mm Hg). The initial step in the modeling analysis was that the circulation was optimized...

...Dinesh A. Peter; Yared Alemu; Michalis Xenos; Ori Weisberg; Itzhak Avneri; Moshe Eshkol; Tal Oren; Moshe Elazar; Yaron Assaf; Danny Bluestein Drug-resistant hypertensive patients may be treated by mechanical stimulation of stretch-sensitive baroreceptors located in the sinus of carotid arteries...

...D. Liu; N. B. Wood; N. Witt; A. D. Hughes; S. A. Thom; X. Y. Xu The retinal arterial network structure can be altered by systemic diseases such as hypertension and diabetes. In order to compare the energy requirement for maintaining retinal blood flow and vessel wall metabolism between normal...

...Amanda R. Lawrence; Keith J. Gooch Arterial axial strains, present in the in vivo environment, often become reduced due to either bypass grafting or the normal aging process. Since the prevalence of hypertension increases with aging, arteries are often exposed to both decreased axial stretch...

... developed Poiseuille flow, the shear stress is inversely proportional to the cube of the deformed inner radius ( 21 ). Sustained hypertension is modeled by a step increase in blood pressure, while blood flow remains unchanged. The increase in pressure causes an abrupt increase in the inner radius...

... biomechanics prosthetics blood vessels surgery cardiovascular system abdominal aortic aneurysm stent-graft type I endoleaks computational analysis sac pressure hypertension aneurysm rupture risk stent-graft migration wall stress Aneurysms, i.e., local irreversible ballooning, occur...