... in vitro behaviors of primary vascular smooth muscle cells (VSMCs) from the thoracic and abdominal aorta of male and female mice. VSMC contractility was assessed by traction force microscopy (TFM; single cell) and collagen gel contraction (collective) with and without stimulation by transforming growth...

...Dimitrios P. Sokolis; Nausicaa Gouskou; Stavroula A. Papadodima; Stavros K. Kourkoulis This study described the regional distribution of layer-specific residual deformations in fifteen human aortas collected during autopsy. Circumferentially and axially cut strips of standardized dimensions from...

... of its actual zero-stress state. The aim of this study was thus to acquire hitherto unreported quantitative knowledge of axial opening angle and residual stretches in different segments and quadrants of the human aorta according to age and gender. Twenty-three aortas were harvested during autopsy from...

.... , 2016 , “ Losartan Attenuates Degradation of Aorta and Lung Tissue Micromechanics in a Mouse Model of Severe Marfan Syndrome ,” Ann. Biomed. Eng. , 44 ( 10 ), pp. 2994 – 3006 . 10.1007/s10439-016-1616-4 [31] Laurent , V. M. , Hénon , S. , Planus , E. , Fodil , R...

...P. Mythravaruni; Parag Ravindran Oxidation of aorta by hydroxyl radicals produces structural changes in arterial proteins like elastin and collagen. This in turn results in change in the mechanical response of aorta. In this paper, a thermodynamically consistent constitutive model is developed...

..., we compared the biaxial mechanical properties of five central arteries—the ascending thoracic aorta, descending thoracic aorta, suprarenal abdominal aorta, infrarenal abdominal aorta, and common carotid artery—from male and female wild-type and fibulin-5 deficient mice. Results revealed...

...Alexander Rachev; Stephen Greenwald; Tarek Shazly Fig. 7 ( a ) Predicted nonequilibrated axial force and ( b ) Peterson's modulus at physiological loading along the length of the aorta The aim of this study was to find plausible causal links between geometrical, compositional...

..., Differences, and Need for a New Class of Computational Models ,” Annu. Rev. Biomed. Eng. , 10 , pp. 221 – 246 . 10.1146/annurev.bioeng.10.061807.160439 [2] Humphrey , J. D. , and Holzapfel , G. A. , 2012 , “ Mechanics, Mechanobiology, and Modeling of Human Abdominal Aorta and Aneurysms...

... change in cross-sectional area does not usually occur in a normal human aorta; hence, the absence of spatial flow retardation. Thus, using RANS-based CFD [ 17 ], the aim of the present study is to test further Menter's SST transitional turbulence model for flow in a realistic aorta and to compare...

...L. Morris; P. Delassus; A. Callanan; M. Walsh; F. Wallis; P. Grace; T. McGloughlin A Spiral Computerized Tomography (CT) scan of the aorta were obtained from a single subject and three model variations were examined. Computational fluid dynamics modeling of all three models showed variations...

...Suo Jin; John Oshinski; Don P. Giddens Helical flows have been observed in the ascending aorta in vivo , and geometric curvature has been suggested to be a major contributing factor. We employed magnetic resonance imaging (MRI) and velocity mapping to develop a computational model to examine...