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Journal Articles

In Memoriam: Colin Caro 1925–2022

Peter D. Weinberg, Robert C. Schroter, Kim H. Parker, Anthony M. J. Bull, Thomas E. Miller, James E. Moore Jr.
Journal: Journal of Biomechanical Engineering
Article Type: In Memoriam
J Biomech Eng. September 2022, 144(9): 090101.
Paper No: BIO-22-1108
DOI: https://doi.org/10.1115/1.4054836
Published Online: July 18, 2022
View Article titled, In Memoriam: Colin Caro 1925–2022
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Topics: Atherosclerosis, Bioengineering, Biomedicine, Diseases, Engineering teachers, Flow (Dynamics), Fluid mechanics, Physiology, Shear (Mechanics), Shear stress
Journal Articles

In Memoriam: Shmuel Einav, 1942–2022

Danny Bluestein, C. Forbes Dewey, Jr., David Elad, Morteza (Mory) Gharib, Roger D. Kamm, Barry B. Lieber, Susan S. Margulies, Marvin J. Slepian, John Tarbell, Sheldon (Shelly) Weinbaum
Journal: Journal of Biomechanical Engineering
Article Type: In Memoriam
J Biomech Eng. August 2022, 144(8): 080101.
Paper No: BIO-22-1168
DOI: https://doi.org/10.1115/1.4054797
Published Online: June 23, 2022
View Article titled, In Memoriam: Shmuel Einav, 1942–2022
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Topics: Bioengineering, Biomedical engineering, Biomedicine, Cardiovascular system, Casting, Engineering teachers, Diseases, Flow (Dynamics), Mentoring, Collaboration
Journal Articles

Estimation of Regional Pulmonary Compliance in Idiopathic Pulmonary Fibrosis Based on Personalized Lung Poromechanical Modeling

Cécile Patte, Pierre-Yves Brillet, Catalin Fetita, Jean-François Bernaudin, Thomas Gille, Hilario Nunes, Dominique Chapelle, Martin Genet
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. September 2022, 144(9): 091008.
Paper No: BIO-21-1444
DOI: https://doi.org/10.1115/1.4054106
Published Online: March 30, 2022
View Article titled, Estimation of Regional Pulmonary Compliance in Idiopathic Pulmonary Fibrosis Based on Personalized Lung Poromechanical Modeling
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Topics: Displacement, Lung, Diseases, Pressure, Porosity, Modeling
Journal Articles

Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice

Abhay B. Ramachandra, Nicole Mikush, Maor Sauler, Jay D. Humphrey, Edward P. Manning
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081008.
Paper No: BIO-21-1330
DOI: https://doi.org/10.1115/1.4053873
Published Online: March 11, 2022
View Article titled, Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice
Click here to open pdf in another window PDF for Compromised Cardiopulmonary Function in Fibulin-5 Deficient Mice
Topics: Fibers, Lung, Pressure, Pulmonary artery, Stress, Ventilation, Energy storage, Stiffness, Diseases, Vessels
Includes: Supplementary data
Journal Articles

Plasticity and Enzymatic Degradation Coupled With Volumetric Growth in Pulmonary Hypertension Progression

Eun-Ho Lee, Seungik Baek
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2021, 143(11): 111012.
Paper No: BIO-21-1109
DOI: https://doi.org/10.1115/1.4051383
Published Online: July 19, 2021
View Article titled, Plasticity and Enzymatic Degradation Coupled With Volumetric Growth in Pulmonary Hypertension Progression
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Topics: Deformation, Diseases, Energy dissipation, Modeling, Plasticity, Pressure, Stress, Damage, Simulation, Anisotropy
Journal Articles

Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction

Caymen Novak, Megan N. Ballinger, Samir Ghadiali
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. November 2021, 143(11): 110801.
Paper No: BIO-20-1555
DOI: https://doi.org/10.1115/1.4051118
Published Online: July 14, 2021
View Article titled, Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction
Click here to open pdf in another window PDF for Mechanobiology of Pulmonary Diseases: A Review of Engineering Tools to Understand Lung Mechanotransduction
Topics: Diseases, Lung
Journal Articles

Morphological Analysis of the Right Ventricular Endocardial Wall in Pulmonary Hypertension

Alifer Bordones-Crom, Sourav S. Patnaik, Prahlad G. Menon, Srinivas Murali, Ender Finol
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. July 2021, 143(7): 074504.
Paper No: BIO-20-1292
DOI: https://doi.org/10.1115/1.4050457
Published Online: April 2, 2021
View Article titled, Morphological Analysis of the Right Ventricular Endocardial Wall in Pulmonary Hypertension
Click here to open pdf in another window PDF for Morphological Analysis of the Right Ventricular Endocardial Wall in Pulmonary Hypertension
Topics: Shapes, Statistical analysis, Pressure, Geometry, Diseases, Cardiac cycle, Pulmonary artery, Image segmentation
Journal Articles

A Brief on Biological Thermodynamics for Human Physiology

Abhijit Dutta, Himadri Chattopadhyay
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. July 2021, 143(7): 070802.
Paper No: BIO-20-1401
DOI: https://doi.org/10.1115/1.4050458
Published Online: April 2, 2021
View Article titled, A Brief on Biological Thermodynamics for Human Physiology
Click here to open pdf in another window PDF for A Brief on Biological Thermodynamics for Human Physiology
Topics: Entropy, Exergy, Physiology, Thermodynamics, Temperature, Diseases, Cardiovascular system
Journal Articles

Correlation of Computational Instantaneous Wave-Free Ratio With Fractional Flow Reserve for Intermediate Multivessel Coronary Disease

Arash Ghorbanniahassankiadeh, David S. Marks, John F. LaDisa, Jr.
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. May 2021, 143(5): 051011.
Paper No: BIO-20-1056
DOI: https://doi.org/10.1115/1.4049746
Published Online: March 8, 2021
View Article titled, Correlation of Computational Instantaneous Wave-Free Ratio With Fractional Flow Reserve for Intermediate Multivessel Coronary Disease
Click here to open pdf in another window PDF for Correlation of Computational Instantaneous Wave-Free Ratio With Fractional Flow Reserve for Intermediate Multivessel Coronary Disease
Topics: Boundary-value problems, Coronary arteries, Diseases, Flow (Dynamics), Waves, Simulation, Computer-aided design, Computational fluid dynamics, Physiology
Journal Articles

The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction

Mostafa Mahmoudi, Ali Farghadan, Daniel R. McConnell, Alex J. Barker, Jolanda J. Wentzel, Matthew J. Budoff, Amirhossein Arzani
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. April 2021, 143(4): 041002.
Paper No: BIO-20-1283
DOI: https://doi.org/10.1115/1.4049026
Published Online: December 14, 2020
View Article titled, The Story of Wall Shear Stress in Coronary Artery Atherosclerosis: Biochemical Transport and Mechanotransduction
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Topics: Atherosclerosis, Coronary arteries, Oxygen, Proteins, Shear stress, Density, Endothelial cells, Permeability, Diseases, Computational fluid dynamics
Journal Articles

GBT440 Increases Hematocrit and Improves Biventricular Function in Berkeley Sickle Cell Disease Mice

Ryan Gassner, David Schreier, Timothy Hacker, Diana M. Tabima, Naomi Chesler
Journal: Journal of Biomechanical Engineering
Article Type: Technical Briefs
J Biomech Eng. March 2021, 143(3): 034501.
Paper No: BIO-20-1168
DOI: https://doi.org/10.1115/1.4049079
Published Online: December 10, 2020
View Article titled, GBT440 Increases Hematocrit and Improves Biventricular Function in Berkeley Sickle Cell Disease Mice
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Topics: Diseases, Polymerization, Blood, Erythrocytes, Statistical analysis, Vehicles
Journal Articles

Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool

Kimberly A. Stevens Boster, Melody Dong, Jessica M. Oakes, Chiara Bellini, Vitaliy L. Rayz, John F. LaDisa, Jr., Dave Parker, Nathan M. Wilson, Shawn C. Shadden, Alison L. Marsden, Craig J. Goergen
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. November 2020, 142(11): 111008.
Paper No: BIO-20-1136
DOI: https://doi.org/10.1115/1.4047479
Published Online: September 9, 2020
View Article titled, Integrated Image-Based Computational Fluid Dynamics Modeling Software as an Instructional Tool
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Topics: Computational fluid dynamics, Computer software, Modeling, Simulation, Students, Cardiovascular system, Boundary-value problems, Diseases
Journal Articles

The Effects of Stiffness, Fluid Viscosity, and Geometry of Microenvironment in Homeostasis, Aging, and Diseases: A Brief Review

Seungman Park, Wei-Hung Jung, Matthew Pittman, Junjie Chen, Yun Chen
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. October 2020, 142(10): 100804.
Paper No: BIO-20-1105
DOI: https://doi.org/10.1115/1.4048110
Published Online: August 31, 2020
View Article titled, The Effects of Stiffness, Fluid Viscosity, and Geometry of Microenvironment in Homeostasis, Aging, and Diseases: A Brief Review
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Topics: Stiffness, Viscosity, Fluids, Diseases, Cancer
Journal Articles

The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease

Richard D. H. Tran, Mark Siemens, Cecilia H. H. Nguyen, Alexander R. Ochs, Michael V. Zaragoza, Anna Grosberg
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. June 2020, 142(6): 061002.
Paper No: BIO-19-1042
DOI: https://doi.org/10.1115/1.4044091
Published Online: January 23, 2020
View Article titled, The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease
Click here to open pdf in another window PDF for The Effect of Cyclic Strain on Human Fibroblasts With Lamin A/C Mutations and Its Relation to Heart Disease
Topics: Diseases, Fibroblasts, Statistical analysis, Membranes, Skin
Includes: Supplementary data
Journal Articles

Temporomandibular Joint Bioengineering Conference: Working Together Toward Improving Clinical Outcomes

Alejandro J. Almarza, Louis G. Mercuri, Boaz Arzi, Luigi M. Gallo, Eric Granquist, Sunil Kapila, Michael S. Detamore
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. February 2020, 142(2): 020801.
Paper No: BIO-19-1034
DOI: https://doi.org/10.1115/1.4044090
Published Online: October 9, 2019
View Article titled, Temporomandibular Joint Bioengineering Conference: Working Together Toward Improving Clinical Outcomes
Click here to open pdf in another window PDF for Temporomandibular Joint Bioengineering Conference: Working Together Toward Improving Clinical Outcomes
Topics: Arthroplasty, Bioengineering, Biomechanics, Bone, Diseases, Osteoarthritis, Performance, Tissue engineering, Cartilage, Damage
Journal Articles

Relative Contributions of Matrix and Myocytes to Biaxial Mechanics of the Right Ventricle in Pulmonary Arterial Hypertension

Daniela Vélez-Rendón, Erica R. Pursell, Justin Shieh, Daniela Valdez-Jasso
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091011.
Paper No: BIO-19-1111
DOI: https://doi.org/10.1115/1.4044225
Published Online: August 2, 2019
View Article titled, Relative Contributions of Matrix and Myocytes to Biaxial Mechanics of the Right Ventricle in Pulmonary Arterial Hypertension
Click here to open pdf in another window PDF for Relative Contributions of Matrix and Myocytes to Biaxial Mechanics of the Right Ventricle in Pulmonary Arterial Hypertension
Topics: Anisotropy, Biological tissues, Mechanical properties, Mechanical testing, Myocardium, Outflow, Stress, Hemodynamics, Modeling, Stiffness
Journal Articles

Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat Using Three-Dimensional Cine DENSE Cardiovascular Magnetic Resonance

Xiaoyan Zhang, Zhan-Qiu Liu, Dara Singh, David K. Powell, Charles S. Chung, Kenneth S. Campbell, Jonathan F. Wenk
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 060904.
Paper No: BIO-18-1025
DOI: https://doi.org/10.1115/1.4041042
Published Online: April 22, 2019
View Article titled, Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat Using Three-Dimensional Cine DENSE Cardiovascular Magnetic Resonance
Click here to open pdf in another window PDF for Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat Using Three-Dimensional Cine DENSE Cardiovascular Magnetic Resonance
Topics: Cardiovascular system, Magnetic resonance, Torsion, Shear (Mechanics), Myocardium, Diseases
Journal Articles

A Numerical Study of Sensitivity Coefficients for a Model of Amyloid Precursor Protein and Tubulin-Associated Unit Protein Transport and Agglomeration in Neurons at the Onset of Alzheimer's Disease

I. A. Kuznetsov, A. V. Kuznetsov
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. March 2019, 141(3): 031006.
Paper No: BIO-18-1293
DOI: https://doi.org/10.1115/1.4041905
Published Online: January 18, 2019
View Article titled, A Numerical Study of Sensitivity Coefficients for a Model of Amyloid Precursor Protein and Tubulin-Associated Unit Protein Transport and Agglomeration in Neurons at the Onset of Alzheimer's Disease
Click here to open pdf in another window PDF for A Numerical Study of Sensitivity Coefficients for a Model of Amyloid Precursor Protein and Tubulin-Associated Unit Protein Transport and Agglomeration in Neurons at the Onset of Alzheimer's Disease
Topics: Diseases, Proteins, Sensitivity analysis, Agglomeration (Materials), Modeling
Includes: Supplementary data
Journal Articles

Computational Fluid Dynamics of Vascular Disease in Animal Models

Andrea Acuna, Alycia G. Berman, Frederick W. Damen, Brett A. Meyers, Amelia R. Adelsperger, Kelsey C. Bayer, Melissa C. Brindise, Brittani Bungart, Alexander M. Kiel, Rachel A. Morrison, Joseph C. Muskat, Kelsey M. Wasilczuk, Yi Wen, Jiacheng Zhang, Patrick Zito, Craig J. Goergen
Journal: Journal of Biomechanical Engineering
Article Type: Review Articles
J Biomech Eng. August 2018, 140(8): 080801.
Paper No: BIO-17-1451
DOI: https://doi.org/10.1115/1.4039678
Published Online: July 12, 2018
View Article titled, Computational Fluid Dynamics of Vascular Disease in Animal Models
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Topics: Computational fluid dynamics, Aneurysms, Hemodynamics, Diseases, Flow (Dynamics), Modeling, Atherosclerosis, Simulation
Journal Articles

A New Growth Model for Aortic Valve Calcification

Rotem Halevi, Ashraf Hamdan, Gil Marom, Karin Lavon, Sagit Ben-Zekry, Ehud Raanani, Rami Haj-Ali
Journal: Journal of Biomechanical Engineering
Article Type: Research-Article
J Biomech Eng. October 2018, 140(10): 101008.
Paper No: BIO-17-1603
DOI: https://doi.org/10.1115/1.4040338
Published Online: June 21, 2018
View Article titled, A New Growth Model for Aortic Valve Calcification
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Topics: Biological tissues, Shapes, Stress, Valves, Diseases, Computerized tomography, Fibers, Tension, Algorithms