It is possible to inject highly supersaturated aqueous solutions of gas through a small capillary into an aqueous environment without the formation of significant gas bubbles. Such a technique has considerable potential therapeutic value in the treatment, for example, of heart attacks and strokes. The present paper is the second in a series (see Brereton et al. 1) investigating the basic phenomenon behind this surprising effect. Recent experiments clearly demonstrate that the nucleation, when it does occur, results from heterogeneous nucleation on the interior surface of the distal end of the capillary. This paper describes the effects of the treatment of this interior surface on the nucleation processes and the results of high speed video observations of the phenomena. A heterogeneous nucleation model is presented which is in accord with the experimental observations.
Skip Nav Destination
Article navigation
December 2002
Technical Papers
Injection of Highly Supersaturated Oxygen Solutions Without Nucleation
J. Creech,
J. Creech
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
Search for other works by this author on:
V. Divino,
V. Divino
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
Search for other works by this author on:
W. Patterson,
W. Patterson
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
Search for other works by this author on:
P. J. Zalesky,
P. J. Zalesky
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
Search for other works by this author on:
C. E. Brennen
C. E. Brennen
California Institute of Technology, MC 104-44, Pasadena, CA 91125
Search for other works by this author on:
J. Creech
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
V. Divino
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
W. Patterson
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
P. J. Zalesky
TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612
C. E. Brennen
California Institute of Technology, MC 104-44, Pasadena, CA 91125
Contributed by the Bioengineering Division for publication in the JOURNAL OF BIOMECHANICAL ENGINEERING. Manuscript received Jul. 2001; revised manuscript received Jun. 2002. Associate Editor: J. B. Grotberg.
J Biomech Eng. Dec 2002, 124(6): 676-683 (8 pages)
Published Online: December 27, 2002
Article history
Received:
July 1, 2001
Revised:
June 1, 2002
Online:
December 27, 2002
Citation
Creech , J., Divino , V., Patterson , W., Zalesky , P. J., and Brennen, C. E. (December 27, 2002). "Injection of Highly Supersaturated Oxygen Solutions Without Nucleation ." ASME. J Biomech Eng. December 2002; 124(6): 676–683. https://doi.org/10.1115/1.1519558
Download citation file:
Get Email Alerts
Cited By
Related Articles
A Statistical Model of Bubble Coalescence and Its Application to Boiling Heat Flux Prediction—Part II: Experimental Validation
J. Heat Transfer (December,2009)
Microscale bubble nucleation from an artificial cavity in single microchannel
J. Heat Transfer (August,2003)
Nucleation and Bubble Dynamics In Vortical Flows
J. Fluids Eng (September,2000)
Related Proceedings Papers
Related Chapters
Phase Field/Fluctuating Hydrodynamics Approach for Bubble Nucleation
Proceedings of the 10th International Symposium on Cavitation (CAV2018)
Nucleation of Bubbles in Perfluoropentane Droplets Under Ultrasonic Excitation
Proceedings of the 10th International Symposium on Cavitation (CAV2018)
In Situ Observations of the Failure Mechanisms of Hydrided Zircaloy-4
Zirconium in the Nuclear Industry: 20th International Symposium