Blood Flow in Abdominal Aortic Aneurysms: Pulsatile Flow Hemodynamics

[+] Author and Article Information
Ender A. Finol, Cristina H. Amon

Mechanical Engineering, Biomedical and Health Engineering; and Institute for Complex Engineered Systems, Carnegie Mellon University, Pittsburgh, PA 15213-3890

J Biomech Eng 123(5), 474-484 (May 15, 2001) (11 pages) doi:10.1115/1.1395573 History: Received September 30, 1999; Revised May 15, 2001
Copyright © 2001 by ASME
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Representation of the axisymmetric model of the two-aneurysm abdominal aorta, for which L1=2.5D,L2=5D,LT=11.25D,D1=2D, and D2=2.75D
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Pulsatile volumetric flow rate (Q) and instantaneous Reynolds number (Re) for Rem=300. Flow stages A,B,[[ellipsis]],I are of particular importance for the evaluation of hemodynamic indicators. Peak systolic flow occurs at t=0.31 s and diastolic phase begins at t=0.52 s.
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Axisymmetric two-aneurysm spectral element mesh: (a) macroelement discretization, and (b) local element decomposition
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Temporal evolution of the axial velocity for Rem=100 at history points #4 and #5 (shown in Fig. 1) of the computational domain
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Streamlines for pulsatile flow at: (a) Rem=100, (b) Rem=200, and (c) Rem=300. The direction of the flow is from left to right.
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Wall pressure variation for Rem=300: (a) spatial distribution at B(t=0.28 s) and E(t=0.50 s); (b) temporal evolution at six different locations on the arterial wall
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Wall shear stress distribution for Rem=300 as a function of time and axial location
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Spatial variation of wall shear stresses for different time-average Reynolds numbers at C(t=0.32 s)
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Wall Shear Stress Gradient (WSSG) distribution for Rem=300 as a function of time and axial location
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Spatial variation of wall shear stress gradients for different time-average Reynolds numbers at C(t=0.32 s)
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Comparison of wall hemodynamics as a function of time-average Reynolds number for steady and pulsatile flow at C(t=0.32 s): (a) maximum wall shear stress; (b) maximum wall shear stress gradient
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Pulsatile volumetric flow rate (Q) and instantaneous Reynolds number (Re) for Rem=50, corresponding to: (a) Mills’ 34 physiological resting curve obtained from velocity probe measurements and (b) Maier’s 38 in-vivo flow curve obtained using an MRI technique. Flow stages (1)–(5) are described in the Conclusions section and also apply to Fig. 2.
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Streamlines for pulsatile flow at Rem=50 resulting from the application of: (a) Mills’ resting curve and (b) Maier’s in-vivo curve. The direction of the flow is from left to right.
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Wall shear stress distributions at stage C (near peak flow) for Rem=50 resulting from the application of Mills’ (stage C1) and Maier’s (stage C2) curves. Peak flow is achieved at different times in each flow curve.
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Wall shear stress distribution for Rem=50 as a function of time and axial location for: (a) Mills’ flow curve and (b) Maier’s flow curve



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