Research Papers

Performance of Self-Expanding Nitinol Stent in a Curved Artery: Impact of Stent Length and Deployment Orientation

[+] Author and Article Information
Shijia Zhao

Department of Mechanical and Materials Engineering,  University of Nebraska-Lincoln, Lincoln, NE, 68588-0656

Linxia Gu1

Department of Mechanical and Materials Engineering,  University of Nebraska-Lincoln, Lincoln, NE 68588-0656;  Nebraska Center for Materials and Nanoscience, Lincoln, NE, 68588-0656lgu2@unl.edu

Stacey R. Froemming

 Hybrid Catheterization and Electrophysiology Laboratory, Children’s Hospital and Medical Center, Omaha, NE, 68114-4133


Corresponding author.

J Biomech Eng 134(7), 071007 (Jul 17, 2012) (6 pages) doi:10.1115/1.4007095 History: Received January 12, 2012; Revised June 03, 2012; Posted July 06, 2012; Published July 17, 2012; Online July 17, 2012

The primary aim of this work was to investigate the performance of self-expanding Nitinol stents in a curved artery through finite element analysis. The interaction between a PROTÉGÉTM GPSTM self-expanding Nitinol stent and a stenosed artery, as well as a sheath, was characterized in terms of acute lumen gain, stent underexpansion, incomplete stent apposition, and tissue prolapse. The clinical implications of these parameters were discussed. The impact of stent deployment orientation and the stent length on the arterial wall stress distribution were evaluated. It was found that the maximum principal stress increased by 17.46%, when the deployment orientation of stent was varied at a 5 deg angle. A longer stent led to an increased contact pressure between stent and underlying tissue, which might alleviate the stent migration. However, it also caused a severe hinge effect and arterial stress concentration correspondingly, which might aggravate neointimal hyperplasia. The fundamental understanding of the behavior of a self-expanding stent and its clinical implications will facilitate a better device design.

Copyright © 2012 by American Society of Mechanical Engineers
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Figure 1

Sectional view of the sheath-restrained Nitinol stent in a curved artery

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Figure 2

PROTÉGÉTM GPSTM self-expanding Nitinol stent partially deployed from the sheath and its microscopic image

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Figure 3

The stress-strain relationship for artery

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Figure 4

The hysteresis behavior of Nitinol obtained from Abaqus

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Figure 5

The deformation of the artery, plaque, and stent in the curved stenosed artery

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Figure 6

The cross section of stenosed artery at site of narrowest occlusion. (a) before stenting; (b) after stenting. Where D denotes the inner diameter of the artery, tmin and tmax are the plaque thickness at its thin and thick side, respectively.

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Figure 7

Arterial stress distributions after stent deployment. (a) catheter along the center of the lumen; (b) tilted catheter with 5 deg angle counterclockwise.

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Figure 8

The influence of stent length on arterial wall stress. (a) “Stent U9,” (b) “Stent U11,” and (c) “Stent U13”.



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