Method and Apparatus for Soft Tissue Material Parameter Estimation Using Tissue Tagged Magnetic Resonance Imaging

[+] Author and Article Information
Kevin F. Augenstein, Ian J. LeGrice, Poul M. F. Nielsen, Alistair A. Young

Bioengineering Institute, The University of Auckland, Private Bag 92019, Auckland, New Zealand

Brett R. Cowan

Department of Medicine The University of Auckland, Private Bag 92019, Auckland, New Zealand

J Biomech Eng 127(1), 148-157 (Mar 08, 2005) (10 pages) doi:10.1115/1.1835360 History: Online March 08, 2005
Copyright © 2005 by ASME
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Grahic Jump Location
A schematic showing the design of the apparatus used for both the gel and isolated heart inflation experiments. All electrical equipment was required to be outside the scanner room. Open loop control was used to control the piston pump. A TTL pulse was sent from the control unit at the commencement of each cycle. This pulse was converted to a triangle pulse to trigger the scanner image acquisition.
Grahic Jump Location
Typical axial SPAMM tagged images showing inflation of the deformable silicon gel phantom. The long axis of the phantom is aligned vertically in the image. Region A is water inside the inner cavity, region B is the silicon gel annulus, and region C is water outside the gel phantom. Note tag fading in the gel relative to free water outside the gel, due to the shorter gel T1 relaxation time constant. Dark and light lines denote inner and outer boundaries, respectively, and points denote tracked tag saturation stripes. (a) Zero relative internal pressure; (b) 3.1 kPa relative internal pressure.
Grahic Jump Location
Radial displacement profile at the centerline with various mesh resolutions for the cylindrical gel phantom model. The legend refers to the number of elements in the circumferential, longitudinal, and radial directions, respectively. All models overlie the 8×4×1 model, except the 4×1×1 model.
Grahic Jump Location
Tagged MRI from the isolated heart passive inflation. Dark lines denote endocardial myocardial LV boundaries and light lines denote epicardial LV boundaries. Points denote tracked tag stripe points. (a) Short axis 0 kPa; (b) short axis 1.5 kPa, (c) long axis 0 kPa; (d) long axis 1.5 kPa.
Grahic Jump Location
The dynamic pressure–volume relationship for the passively inflated heart, inflated with a period of 1.5 s
Grahic Jump Location
SPAMM tagged image and gel phantom finite element model. The color map shows the circumferential extension ratio, while lines show boundaries of the phantom model.
Grahic Jump Location
(a) Plan view of the rotational shear test apparatus. Moment couple F is applied to the outer cylinder, which is free to rotate with respect to the inner (fixed) cylinder. (b) Rotational shear test results for four different loading states and 15 radial positions. The plot shows the normalized data and fitted curve (slope C1=8.72 kPa;R2=0.9974).
Grahic Jump Location
(a) Fiber angle (defined as the angle to the imaging plane) calculated from diffusion imaging. Gray is parallel to the image plane. The fitted fiber angles on the fitted LV geometry. A linear basis was used through the wall, and three different transmural locations are shown here, starting on the left the endocardial fibers (b), the midwall (c), and the epicardial fibers (d).



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