RESEARCH PAPERS: Other Research Papers

Gas Transport in Serpentine Microporous Tubes Under Steady and Pulsatile Blood Flow Conditions

[+] Author and Article Information
Kazuo Tanishita, Masanobu Ujihira, Akihisa Watabe, Kunio Nakano, Peter D. Richardson, Pierre M. Galletti

Department of Mechanical Engineering, Keio University, Yokohama, Japan, Tokyo Women’s Medical College, Tokyo, Japan, and Brown University, Providence, Rhode Island

J Biomech Eng 113(2), 223-229 (May 01, 1991) (7 pages) doi:10.1115/1.2891238 History: Received June 01, 1988; Revised December 01, 1990; Online March 17, 2008


A serpentine gas exchange unit was built with cylindrical tubular microporous membranes featuring periodic arcs with a fixed curvature ratio (ratio of tube radius to radius of curvature) of 1/14 and circular angles between 30 and 360 deg. Oxygen transfer was measured under steady and pulsatile blood flow conditions in vitro and ex vivo to assess the design features which most effectively augment gas transfer. Under steady blood flow conditions, oxygen transfer increased with circular angles beyond 70 deg. Under pulsatile conditions, a wide range of geometrical and fluid mechanical parameters could be combined to enhance gas transfer performance, which eventually depended upon the secondary Reynolds number and the Womersley parameter.

Copyright © 1991 by The American Society of Mechanical Engineers
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