Simultaneous Convective and Diffusive Mass Transfers in a Hemodialyser

[+] Author and Article Information
Michel Y. Jaffrin, Luhui Ding, Jean Marc Laurent

Department of Biological Engineering, University of Technology of Compiègne, 60206 Compiegne Cedex, France

J Biomech Eng 112(2), 212-219 (May 01, 1990) (8 pages) doi:10.1115/1.2891174 History: Received July 07, 1989; Revised February 01, 1990; Online March 17, 2008


The mass transfer in a hemodialyser in the presence of combined dialysis and ultrafiltration has been calculated by integration of mass fluxes across the boundary layers in blood and dialysate phase taking into account the partial rejection of solute as well as changes in local blood flow and ultrafiltration flux along the membrane. Clearances of creatinin, vitamin B12, and myoglobin have been calculated as a function of blood and ultrafiltrate flow rate and were found to be in good agreement with in vitro measurements. The data suggest the following empirical correlation for the hemodiafiltration clearance

CL = CLD + 0.46QF
where Q F is the ultrafiltration flow rate and C LD is the clearance at Q F =0.

Copyright © 1990 by The American Society of Mechanical Engineers
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