Small-Scale Temperature Fluctuations in Perfused Tissue During Local Hyperthermia

[+] Author and Article Information
J. W. Baish, P. S. Ayyaswamy

Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, Philadelphia, Pa. 19104

K. R. Foster

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pa. 19104

J Biomech Eng 108(3), 246-250 (Aug 01, 1986) (5 pages) doi:10.1115/1.3138610 History: Received May 28, 1985; Revised May 01, 1986; Online June 12, 2009


We develop analytical expressions (scaling laws) for the local temperature fluctuations near isolated and countercurrent blood vessels during hyperthermia. These scaling laws relate the magnitude of such fluctuations to the size of the heated region and to the thermal equilibration length of the vessels. A new equilibration length is identified for countercurrent vessels. Significant temperature differences are predicted between the vessels and the immediately adjacent tissue when the equilibration length is comparable to or longer than the size of the heated tissue region. Countercurrent vessels are shown to have shorter equilibration lengths and produce smaller temperature fluctuations than isolated vessels of the same size.

Copyright © 1986 by ASME
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