Mechanical Characterization of Membranelike Biological Tissue

[+] Author and Article Information
L. E. Thibault

Department of Bioengineering, University of Pennsylvania, Philadelphia, Pa. 19104

D. L. Fry

Laboratory of Experimental Atherosclerosis, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md.; and Laboratory of Experimental Atherosclerosis, The Ohio State Unversity, College of Medicine, Columbus, Ohio 43210

J Biomech Eng 105(1), 31-38 (Feb 01, 1983) (8 pages) doi:10.1115/1.3138381 History: Received November 11, 1981; Revised August 17, 1982; Online June 15, 2009


Experimental and analytical methods are presented which enable one to examine the local rheological properties of biological tissues which can be captured as flat sheets between matching pressure manifolds and deformed under experimentally prescribed hydrostatic loading conditions. In spite of the fact that most biological tissues, including arteries, are nonlinearly elastic when considered over wide ranges of strain, it was found that the deformation of swine and canine arterial wall specimens in the physiological range of wall strain can be approximated by an isotropic, linearily elastic membrane model. In view of this, the elastic behavior was characterized approximately by an incremental modulus over the range of 0.45 to 0.65 strain. The incremental modulus in both species was shown to increase by a factor of three along the descending thoracic aorta from the ductus scar to the celiac orifice.

Copyright © 1983 by ASME
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