Hemodynamic Measurements in Human Arterial Casts, and Their Correlation With Histology and Luminal Area

[+] Author and Article Information
M. H. Friedman, C. B. Bargeron, F. F. Mark, O. J. Deters

The Johns Hopkins University, Applied Physics Laboratory, Laurel, Md. 20810

G. M. Hutchins

The Johns Hopkins University, School of Medicine, Baltimore, Md. 21205

J Biomech Eng 102(3), 247-251 (Aug 01, 1980) (5 pages) doi:10.1115/1.3149581 History: Received August 01, 1979; Revised May 02, 1980; Online June 15, 2009


A new approach is presented for studying the vascular response to hemodynamic stress. A laser doppler anemometer is used to make velocity measurements very near the walls of human arterial casts; these measurements are then correlated with the histology of the artery from which the cast was made. Several illustrative results are given which suggest that the velocity profiles along the outer walls of aortic bifurcations may be significantly determined by the longitudinal variation of cross-sectional area. The shapes of these profiles were qualitatively different for each cast studied. In one specimen, the location of initial lipid deposits appeared to correlate with flow acceleration.

Copyright © 1980 by ASME
Your Session has timed out. Please sign back in to continue.





Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In