A Miniature Toposcopic Catheter Suitable for Small Diameter Tortuous Blood Vessels

[+] Author and Article Information
S. R. Goldstein, R. E. Jones, J. W. Boretos

Biomedical Engineering and Instrumentation Branch, Division of Research Services, National Institutes of Health, Bethesda, Md. 20014

J. J. Sipe

Biosearch, Inc., Raritan, N.J.

J. L. Doppman

Diagnostic Radiology Branch, Clinical Center, National Institutes of Health, Bethesda, Md. 20014

J Biomech Eng 102(3), 221-229 (Aug 01, 1980) (9 pages) doi:10.1115/1.3149577 History: Received November 06, 1979; Online June 15, 2009


A miniature catheter suitable for clinical use based on the principle of the continuously everting tube has been developed and tested extensively in dogs. The 1-mm-dia flexible tube can advance up a narrow tortuous blood vessel 30 cm beyond the tip of the conventional catheter to which it is attached. A slippery hydromer coating combined with a U-shaped cross section enables the tube eversion to be accomplished at an acceptable operating pressure. The new system will provide access to previously inaccessible regions of the body, and has the potential for clinical use in embolizing selected vessels, providing highly localized chemotherapy, and sampling body fluids. The catheter can advance both with and against the blood flow in arteries and veins, and is awaiting clinical trials.

Copyright © 1980 by ASME
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