Nonlinear Constitutive Relations for Human Brain Tissue

[+] Author and Article Information
M. R. Pamidi

Sargent & Lundy Engineers, Chicago, Ill.; General Motors Corporation, Electro-Motive Division, La Grange, Ill.

S. H. Advani

West Virginia University, Morgantown, W. Va.

J Biomech Eng 100(1), 44-48 (Feb 01, 1978) (5 pages) doi:10.1115/1.3426188 History: Received September 12, 1977; Online October 21, 2010


Head injury modeling studies warrant detailed investigations into the rheological behavior of brain tissue. This paper deals with the development of the concept of a power function and employs energy principles to derive nonlinear constitutive relations for human brain tissue. Nonlinear discrete and continuum models are constructed and it is found that the model predictions compare well with experimentally determined in-vitro properties of human brain tissue under uniaxial loading conditions.

Copyright © 1978 by ASME
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