Meniscal injury has been found to leave patients at high risk for the development of knee osteoarthritis (OA). Partial meniscectomy is often used to treat meniscal tears, and while this procedure adequately addresses pain and the restoration of function, it does not prevent the progression of OA in the injured knee. Often during arthroscopy, surgeons identify areas of “softened” cartilage, which do not always correlate with visible signs of surface damage or cartilage loss. This softening has been related to changes in the cartilage matrix, which could represent early structural damage that can lead to irreversible cartilage damage and OA.

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