Block copolymer-based membrane technology represents a versatile class of nanoscale materials in which biomolecules, such as membrane proteins, can be reconstituted. Among its many advantages over conventional lipid-based membrane systems, block copolymers can mimic natural cell biomembrane environments in a single chain, enabling large-area membrane fabrication using methods like Langmuir-Blodgett deposition, or spontaneous protein-functionalized nanovesicle formation. Based on this unique membrane property, a wide variety of membrane proteins possessing unique functionalities including pH/voltage gatable porosity, photon-activated proton pumping, and gradient-dependent production of electricity have been successfully inserted into these biomimetic systems.
Fabrication of Hybrid Bionanodevices Based on Coupled Protein Functionality
Ho, D, Chu, B, Lee, H, Kuo, K, & Montemagno, CD. "Fabrication of Hybrid Bionanodevices Based on Coupled Protein Functionality." Proceedings of the ASME 2004 3rd Integrated Nanosystems Conference. Design, Synthesis, and Applications. Pasadena, California, USA. September 22–24, 2004. pp. 1-6. ASME. https://doi.org/10.1115/NANO2004-46012
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