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Review Article

SINGLE-CELL ANALYSIS USING HYPERSPECTRAL IMAGING MODALITIES

[+] Author and Article Information
Nishir Mehta

Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803
nmehta3@lsu.edu

Shahensha Shaik

Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803
sshaik4@lsu.edu

Ram Devireddy

Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803
rdevir1@lsu.edu

Manas Gartia

Department of Mechanical Engineering, Louisiana State University, Baton Rouge, LA 70803
mgartia@lsu.edu

1Corresponding author.

ASME doi:10.1115/1.4038638 History: Received June 17, 2017; Revised November 22, 2017

Abstract

Almost a decade ago, Hyperspectral Imaging (HSI) was employed by the NASA in satellite imaging applications such as remote sensing technology. This technology has since been extensively used in the exploration of minerals, agricultural purposes, water resources, and urban development needs. Due to recent advancements in optical re-construction and imaging, HSI can now be appliedtranslated down to micro- and nano-meter scales possibly allowing for exquisite control and analysis of single cell to complex biological systems. This short review provides a description of the working principle of the HSI technology and how HSI can be used to assist, by substitute and validate traditional imaging technologies. This is followed by a description of the use of HSI for biological analysis and medical diagnostics with special emphasis on single cell analysis using HSI.

Copyright (c) 2017 by ASME
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