0
research-article

Poisson Contraction and Fiber Kinematics in Tissue: Insight from Collagen Network Simulations

[+] Author and Article Information
Catalin Picu

Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180
picuc@rpi.edu

Sai Deogekar

Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180
deoges@rpi.edu

Mohammad Islam

Department of Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180
islamm3@rpi.edu

1Corresponding author.

ASME doi:10.1115/1.4038428 History: Received June 10, 2017; Revised November 01, 2017

Abstract

Connective tissue mechanics is highly non-linear, exhibits a strong Poisson effect and is associated with significant collagen fiber re-arrangement. Although the general features of the stress-strain behavior in tension and compression and under uniaxial, biaxial and shear loading have been discussed extensively, especially from the macroscopic perspective, the Poisson effect and the kinematics of filaments have received less attention. In general, the relationship between the microscopic fiber network mechanics and the macroscopic experimental observations remains poorly defined. The objective of the present work is to provide additional insight into this relationship. To this end, results from models of random collagen networks are compared with experimental data on reconstructed collagen gels, mouse skin dermis and the human amnion. Attention is devoted to the mechanism leading to the large Poisson effect observed in experiments. The effect of fiber tortuosity on network mechanics is also discussed. A comparison of biaxial and uniaxial loading response is performed. Such model validation is essential since these can be used to evaluate parameters important in tissue mechanics which are not accessible experimentally.

Copyright (c) 2017 by ASME
Your Session has timed out. Please sign back in to continue.

References

Figures

Tables

Errata

Discussions

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In