Technical Brief

Extending the Power-Law Hemolysis Model to Complex Flows

[+] Author and Article Information
Mohammad M. Faghih, M. Keith Sharp

Biofluid Mechanics Laboratory,
Department of Mechanical Engineering,
University of Louisville,
Louisville, KY 40292

Manuscript received April 23, 2016; final manuscript received September 9, 2016; published online November 4, 2016. Assoc. Editor: Ender A. Finol.

J Biomech Eng 138(12), 124504 (Nov 04, 2016) (4 pages) Paper No: BIO-16-1170; doi: 10.1115/1.4034786 History: Received April 23, 2016; Revised September 09, 2016

Hemolysis (damage to red blood cells) is a long-standing problem in blood contacting devices, and its prediction has been the goal of considerable research. The most popular model relating hemolysis to fluid stresses is the power-law model, which was developed from experiments in pure shear only. In the absence of better data, this model has been extended to more complex flows by replacing the shear stress in the power-law equation with a von Mises-like scalar stress. While the validity of the scalar stress also remains to be confirmed, inconsistencies exist in its application, in particular, two forms that vary by a factor of 2 have been used. This article will clarify the proper extension of the power law to complex flows in a way that maintains correct results in the limit of pure shear.

Copyright © 2016 by ASME
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