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Technical Briefs

Development of an In Vitro Porcine Aorta Model to Study the Stability of Stent Grafts in Motor Vehicle Accidents

[+] Author and Article Information
Kurosh Darvish1

Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122kdarvish@temple.edu

Mehdi Shafieian, Vasily Romanov

Department of Mechanical Engineering, Temple University, 1947 North 12th Street, Philadelphia, PA 19122

Vittorio Rotella, Michael D. Salvatore, John Blebea

Section of Vascular Surgery, Temple University, 1947 North 12th Street, Philadelphia, PA 19122

1

Corresponding author.

J Biomech Eng 131(4), 044505 (Feb 03, 2009) (4 pages) doi:10.1115/1.2948398 History: Received July 07, 2007; Revised March 06, 2008; Published February 03, 2009

Endovascular stent grafts for the treatment of thoracic aortic aneurysms have become increasingly utilized and yet their locational stability in moderate chest trauma is unknown. A high speed impact system was developed to study the stability of aortic endovascular stent grafts in vitro. A straight segment of porcine descending aorta with stent graft was constrained in a custom-made transparent urethane casing. The specimen was tested in a novel impact system at an anterior inclination of 45deg and an average deceleration of 55G, which represented a frontal automobile crash. Due to the shock of the impact, which was shown to be below the threshold of aortic injury, the stent graft moved 0.6mm longitudinally. This result was repeatable. The presented experimental model may be helpful in developing future grafts to withstand moderate shocks experienced in motor vehicle accidents or other dynamic loadings of the chest.

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Copyright © 2009 by American Society of Mechanical Engineers
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Figures

Grahic Jump Location
Figure 1

Aorta specimen mounted to the linear impact system horizontally and with 45deg anterior inclination. The sliding carriage is pushed by the active track and hits the shock absorber. Aorta was pressurized and mounted on a translucent urethane casing to allow visualization of displacements during the impact. Point T was used to track the rigid body motion of the casing. Points P (at the proximal connection), D (at the distal connection), and S (a suture near the distal end of the stent) were tracked to calculate the specimen displacements with respect to the casing.

Grahic Jump Location
Figure 2

The crash pulse applied to the specimen. After the initial spike, a constant deceleration (about 50G) was achieved for a duration of about 15ms, which represented the crushing of a vehicle.

Grahic Jump Location
Figure 3

The pressure time history of the in vitro model is compared with the aortic pressure in cadaveric frontal crash tests and excised aorta failure pressures (4). The model showed severe but yet subfailure increase in the intra-aortic pressure. The peak pressures were aligned at t=88ms (peak of the average cadaver tests) to allow this comparison.

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