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TECHNICAL BRIEFS

Accumulation of E. Coli Bacteria in Mini-Channel Flow

[+] Author and Article Information
M. S. Mayeed, A. Mian, G. W. Auner

Smart Sensors & Integrated Microsystems (SSIM) Program, College of Engineering, Wayne State University, Detroit, MI 48202

G. M. Newaz

Smart Sensors & Integrated Microsystems (SSIM) Program, College of Engineering, Wayne State University, Detroit, MI 48202gnewaz@eng.wayne.edu

J Biomech Eng 128(3), 458-461 (Nov 18, 2005) (4 pages) doi:10.1115/1.2187049 History: Received February 03, 2005; Revised November 18, 2005

The objective of this research is to design and optimize a mini/micro-channel based surface-accumulator of E. coli bacteria to be detected by acoustic wave biosensors. A computational approach has been carried out using the state of the art software, CFD -ACE with water as bacteria bearing fluid. E. coli bacteria have been modeled as random discrete particles tracked by solving the Lagrangian equations. The design challenges are to achieve low shear force (pico-N), high concentration at accumulation, and high enough Reynolds number to avoid bacteria swimming. A range of low Reynolds number (Re) has been considered along with the effects of particle boundary interactions, gravity, Saffman lift, etc. More than two orders of magnitude higher concentration at the accumulation than the inlet concentration, and lower shear force of less than pico-N have been achieved in the optimized designs.

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Copyright © 2006 by American Society of Mechanical Engineers
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Figures

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Figure 2

Particle accumulation pattern at β=4L and Re=11.7

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Figure 3

Particle accumulation pattern at β=4L and Re=0.12

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Figure 4

Particle accumulation pattern at geometry I with a trap, β=4L and Re=11.7

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Figure 5

Particle accumulation pattern at geometry I with a trap, β=4L and Re=58.3

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Figure 1

U-velocity or x-direction (inlet flow direction) velocity profiles at different cross sections. Here, β=4L and Re=291.

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