Electrical Impedance Tomography of Cell Viability in Tissue With Application to Cryosurgery

[+] Author and Article Information
Rafael Davalos, Boris Rubinsky

Biomedical Engineering Laboratory—Department of Mechanical Engineering, 6178 Etcheverry Hall—University of California at Berkeley, Berkeley CA, 94720-1740

J Biomech Eng 126(2), 305-309 (May 04, 2004) (5 pages) doi:10.1115/1.1695577 History: Received March 27, 2003; Revised July 15, 2003; Online May 04, 2004
Copyright © 2004 by ASME
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Thermal history of liver tissue frozen in air and frozen using liquid nitrogen.
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Schematic of experimental setup.
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Histological samples of rat liver at 200× magnification, showing the nuclei (n) and cytoplasmic limits (c) a: freshly excised sample b: sample frozen with liquid nitrogen c: sample frozen in air.
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First post-cryosurgical configuration: 6 cm imaging domain (1.0ρo) with a 2 cm circular damaged region (0.363ρo) located in the center of the domain a: Simulated phantom b: Generated image.
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Second post-cryosurgical configuration: 6 cm imaging domain (1.0ρo) with a 1.5 cm×2.5 elliptical section and a 1.5 cm circular section that are damaged (0.363ρo)a: Simulated phantom b: Generated image.



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