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TECHNICAL PAPERS

Mechanical Properties of a Reversible, DNA-Crosslinked Polyacrylamide Hydrogel

[+] Author and Article Information
David C. Lin

Department of Mechanical and Aerospace Engineering, Rutgers, The State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854

Bernard Yurke

Bell Laboratories, Lucent Technologies Inc., 600 Mountain Avenue, Murray Hill, NJ 07974

Noshir A. Langrana

Department of Mechanical and Aerospace Engineering, Rutgers, The State University of New Jersey, 98 Brett Road, Piscataway, NJ 08854e-mail: langrana@caip.rutgers.edu

J Biomech Eng 126(1), 104-110 (Mar 09, 2004) (7 pages) doi:10.1115/1.1645529 History: Received September 16, 2002; Revised September 04, 2003; Online March 09, 2004
Copyright © 2004 by ASME
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References

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Figures

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Two polyacrylamide chains crosslinked by three DNA strands (SA1, SA2, and the crosslinking strand L2)
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Sapphire bead in gel preparation from viscosity test
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Elasticity test fixture
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Schematic of the direct compression test
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Viscosity versus temperature at various crosslinker densities
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Photograph of the 33% crosslinked gel on microscope slide
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Elapsed-time comparison of the gel in a solution of removal DNA (top) and in TE buffer (bottom). The diagrams beneath each photograph are schematic representations of the distribution density of the fluorescent spheres.
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A representative force-displacement plot from the magnetic sphere elasticity test
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Elastic modulus versus crosslinker density
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Logarithmic plot of elastic modulus versus normalized crosslinker concentration
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Dissociation of the polymer network by a removal DNA strand

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