Analysis of Prolapse in Cardiovascular Stents: A Constitutive Equation for Vascular Tissue and Finite-Element Modelling

[+] Author and Article Information
P. J. Prendergast, C. Lally, S. Daly, A. J. Reid

Department of Mechanical Engineering, Trinity College, Dublin, Ireland

T. C. Lee

Department of Anatomy, Royal College of Surgeons in Ireland, Dublin, Ireland

D. Quinn, F. Dolan

Medtronic AVE, Parkmore Industrial Estate, Galway, Ireland

J Biomech Eng 125(5), 692-699 (Oct 09, 2003) (8 pages) doi:10.1115/1.1613674 History: Received August 27, 2001; Revised February 10, 2003; Online October 09, 2003
Copyright © 2003 by ASME
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(a) Luminal tissue prolapse within a stented vessel (indicated by black lines)1, (b) A 2-D schematic of a stented vessel before stenting with vessel wall ideally cylindrical and (c) after stenting where the tissue drapes between the stent wiresGrahic Jump Location
Schematic illustration of the biaxial testing device
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Close-up view of a biaxial specimen with the array of dots used to measure stretch and the crocodile clips used to clamp the tissue
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Four types of stent analyzed in this study; (BeStent 2, Medtronic AVE; NIROYAL, Boston Scientific; VELOCITY, Cordis, and the TETRA Stent, Guidant) and a plan view of finite element meshes within an expanded repeating unit. The red arrow indicates the direction and the start point from which the distance around the periphery of the stent is taken.
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Five uniaxial stress-stretch curves for pig aorta, with the fitted elastic model (dashed line)
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Five biaxial stress-stretch curves for pig aorta, with the fitted elastic model (dashed line)
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Uniaxial and biaxial data for the human femoral artery, with the fitted biaxial and uniaxial constitutive models (dashed line)
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The maximum prolapse of the vascular tissue within the repeating unit of the stent for each of the four stents analyzed. The result is given for both the porcine aorta properties and the human femoral properties.
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Prolapse of the four stents: Contour plot of the displacements in the BeStent 2, Medtronic AVE, the NIROYAL, Boston Scientific, the VELOCITY, Cordis; and the Tetra Stent, Guidant
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Maximum principal stress in the mid-layer of the vessel around the periphery of the repeating-unit (i.e., directly above the stent wire). High stresses are indicative of a likelihood of tissue damage and intimal hyperplasia.
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Peak stress vs. mesh type. Mesh type 1: 4 elements through vessel wall; Mesh type 2: 8 elements through vessel wall; Mesh type 3: 12 elements through vessel wall; Mesh type 4: 12 elements through vessel wall, with double the mesh density shown in Fig. 4.



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