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TECHNICAL PAPERS: Fluids/Heat/Transport

Numerical Simulation of Wall Shear Stress Conditions and Platelet Localization in Realistic End-to-Side Arterial Anastomoses

[+] Author and Article Information
P. Worth Longest, Clement Kleinstreuer

Department of Mechanical and Aerospace Engineering, North Carolina State University, Raleigh, NC

J Biomech Eng 125(5), 671-681 (Oct 09, 2003) (11 pages) doi:10.1115/1.1613298 History: Received December 03, 2002; Revised February 07, 2003; Online October 09, 2003
Copyright © 2003 by ASME
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References

Figures

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Geometric surface models of commonly implemented anastomotic configurations. Case A is characterized by a proximally occluded artery, whereas Cases B and C allow for 20% proximal outflow.
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Standard Type I input pulse for a 6 mm graft consistent with typical post-surgical observations of the human femoropopliteal bypass 25 and canine anastomotic models 14
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Validation of the luminal-particle-tracking algorithm in an annular expansion (d1=151 μm;d2=504 μm) under sinusoidal flow conditions. (a) Experimental observation of a red blood cell trajectory 35 released at position A. The left panel illustrates particle motion during the vortex expansion phase (position A to B) while the right panel displays the trajectory during vortex retraction (position B through exit). (b) Corresponding simulation of an idealized spherical blood particle trajectory viewed in two stages (from Ref. 15).
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Outline of the NWRT model for platelets including platelet stimulation history (PSH) and WSS-based surface reactivity (SR) conditions
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Surface contours of the WSS-based hemodynamic parameters for Case A (high graft-angle and no proximal outflow)
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Surface contours of the WSS-based hemodynamic parameters for Case B (high graft-angle and 20% proximal outflow)
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Surface contours of the WSS-based hemodynamic parameters for Case C (low graft-angle and 20% proximal outflow)
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NWRT contours based on platelet trajectories with and without PSH and SR Case A (b) factors. Including the PSH and SR factors, a potential shift in significant IH occurrence is observed from the floor of Case A (b) to the graft hood of Case C (f). The particle hemodynamic potential for IH occurrence appears significant at the heel and along the lateral wall for all cases considered.
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Convergence of the NWRT parameter based on platelet trajectories with and without dispersion. A mean relative error of εmean≤10% has been assumed to represent a sufficiently converged solution, cf. Eq. (9).

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