Passive Biaxial Mechanical Response of Aged Human Iliac Arteries

[+] Author and Article Information
Christian A. J. Schulze-Bauer, Gerhard A. Holzapfel

Institute for Structural Analysis, Computational Biomechanics, Graz University of Technology, 8010 Graz, Schiesstattgasse 14-B, Austria

Christian Mörth

Institute of Pathology, Karl-Franzens-University Graz, 8036 Graz, Auenbruggerplatz 25, Austria

J Biomech Eng 125(3), 395-406 (Jun 10, 2003) (12 pages) doi:10.1115/1.1574331 History: Received January 01, 2001; Revised January 01, 2003; Online June 10, 2003
Copyright © 2003 by ASME
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Human external iliac artery fixed in a Perspex frame (a). Ultrasound image of an arterial cross section (b) with a minor atherosclerotic plaque (this artery was excluded from mechanical testing).
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Photomicrographs of the three wall layers stemming from the gage section of specimen IV after surgical dissection. Cell nuclei appear regular and vital in all layers. The intima shows homogeneous thickening due to diffuse intimal hyperplasia. EEL indicates the external elastic lamina. Hematoxylin and eosin (H-E) staining. Ten-micron thick section. Original magnification 100×.
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Pressure-circumferential stretch plot (a) and pressure-axial stretch plot (b) of specimen IV. Each curve is associated with a specific external axial load. Experimental data, used for least-square fitting, are indicated by closed boxes. Calculated data from the corresponding isotropic-anisotropic split strain-energy function by 23 are represented by open triangles which are connected with dashed lines. The 0N-check (dotted line), performed after “5.90N loading,” shows no significant difference between the initial “0N loading” curve (solid line). Likewise, the third loading cycles (solid lines) of the “9.90N and 5.90N loading” resemble the first loading cycles (dotted lines).
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Representative plot of selected experimental and calculated data of specimen IV in the deformation plane (axial stretch vs. circumferential stretch). Experimental data are indicated by closed circles that are interconnected with parametric lines (thick and solid). Each parametric line is associated with a particular pressure and external axial load, so that all experimental quantities which determine a data point (transmural pressure, external axial load, circumferential and axial stretches) can be studied simultaneously. For comparison purposes the calculated stretches are plotted for the isotropic-anisotropic split model 23 (open boxes, dashed parametric lines) and for the exponential model 18 (closed boxes, dotted parametric lines). The parametric lines of the models are associated with the same pressures and axial loads as the ones of the experimental data.
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Plot of selected experimental data of the loading branches of specimens I, II, IIIb, VII. Data points are at the intersections of parametric lines that specify constant pressures (dashed) and external axial loads (solid). The associated values of the parametric pressures and axial loads are denoted in the data ensemble of specimen I. The parametric lines of the data ensembles of the other specimens correspond to the same values. A clear correlation between age and distensibility of specimens can be seen. For the sake of clarity specimens V and VI, which behave similar as specimen VII, are not included. Specimen IIIa resembles closely IIIb, and data of specimen IV can be viewed in Figs. 4 and 5.




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