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TECHNICAL PAPERS: Soft Tissue

Axial Mechanical Properties of Fresh Human Cerebral Blood Vessels

[+] Author and Article Information
Kenneth L. Monson, Werner Goldsmith

Department of Mechanical Engineering, University of California, Berkeley, CA 94720

Nicholas M. Barbaro, Geoffrey T. Manley

Department of Neurological Surgery, University of California, San Francisco, CA 94143

J Biomech Eng 125(2), 288-294 (Apr 09, 2003) (7 pages) doi:10.1115/1.1554412 History: Received April 01, 2002; Revised November 01, 2002; Online April 09, 2003
Copyright © 2003 by ASME
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References

Thurman,  D. J., Alverson,  C., Dunn,  K. A., Guerrero,  J., and Sniezek,  J. E., 1999, “Traumatic Brain Injury in the United States: A Public Health Perspective,” J. Head Trauma Rehabil., 14(6), pp. 602–615.
Bandak, F. A., and Eppinger, R. H., 1994, “A Three-Dimensional Finite Element Analysis of the Human Brain Under Combined Rotational and Translational Accelerations,” SAE 942215, Proc. 38th STAPP Car Crash Conference, Society of Automotive Engineers.
Vossoughi, J., and Bandak, F. A., 1996, “Mechanical Characteristics of Vascular Tissue and their Role in Brain Injury Modeling: A Review,” Traumatic Brain Injury: Bioscience and Mechanics, F. A. Bandak et al., eds., Mary Ann Liebert Inc., Larchmont, pp. 207–215.
Omori, K., Zhang, L., Yang, K. H., and King, A. I., 2000, “Effect of Cerebral Vasculatures on the Mechanical Response of Brain Tissue: A Preliminary Study,” Crashworthiness, Occupant Protection, and Biomechanics in Transportation Systems ASME 2000, H. F. Mahmood et al., eds., ASME, New York, AMD-Vol. 246/BED-Vol. 49, pp. 167–174.
Stehbens, W. E., 1972, Pathology of the Cerebral Blood Vessels, C. V. Mosby, St. Louis.
Melvin, J. W., Lighthall, J. W., and Ueno, K., 1993, “Brain Injury Biomechanics,” Accidental Injury, A. M. Nahum and J. W. Melvin, eds., Springer-Verlag, New York, pp. 268–291.
Gean, A. D., 1994, Imaging of Head Trauma, Raven Press, New York.
Chalupnik, J. D., Daly, C. H., and Merchant, H. C., 1971, “Material Properties of Cerebral Blood Vessels,” Final Report on Contract No. NIH-69-2232, Report No. ME 71-11, Univ. of Washington, Seattle.
Steiger,  H. J., Aaslid,  R., Keller,  S., and Reulen,  H. J., 1989, “Strength, Elasticity and Viscoelastic Properties of Cerebral Aneurysms,” Heart Vessels, 5(1), pp. 41–46.
Löwenhielm,  P., 1974, “Dynamic Properties of the Parasagittal Bridging Veins,” Z. Rechtsmed, 74, pp. 55–62.
Lee,  M. C., and Haut,  R. C., 1989, “Insensitivity of Tensile Failure Properties of Human Bridging Veins to Strain Rate: Implications in Biomechanics of Subdural Hematoma,” J. Biomech., 22, pp. 537–542.
Meaney, D. F., 1991, “Biomechanics of Acute Subdural Hematoma in the Subhuman Primate and Man,” Dissertation, University of Pennsylvania, Philadelphia.
Mohan,  D., and Melvin,  J. W., 1982, “Failure Properties of Passive Human Aortic Tissue, I-Uniaxial Tension Tests,” J. Biomech., 15, pp. 887–902.
Mohan,  D., and Melvin,  J. W., 1983, “Failure Properties of Passive Human Aortic Tissue, II-Biaxial Tension Tests,” J. Biomech., 16, pp. 31–44.
Löwenhielm,  P., 1978, “Dynamic Strain Tolerance of Blood Vessels at Different Post-Mortem Conditions,” J. Bioeng., 2, pp. 509–515.
Lee, M. C., and Haut, R. C., 1985, “Strain Rate Effects on Tensile Failure Properties of the Human Parasagittal Bridging Vein and the Common Carotid Artery and Jugular Veins of Ferrets,” N. A. Langrana, ed., Advances in Bioengineering, ASME, New York, pp. 111–112.
Fung,  Y. C., 1967, “Elasticity of soft tissues in simple elongation,” Am. J. Physiol., 213, pp. 1532–1544.
Monson, K. L., 2001, “Mechanical and Failure Properties of Human Cerebral Blood Vessels,” Dissertation, University of California, Berkeley.
Yamada, H., 1970, Strength of Biological Materials, F. G. Evans, ed., Williams and Wilkins, Baltimore.
Busby,  D. E., and Burton,  A. C., 1965, “The Effect of Age on the Elasticity of the Major Brain Arteries,” Can. J. Physiol. Pharmacol., 43, pp. 185–202.
Hayashi,  K., Handa,  H., Nagasawa,  S., Okumura,  A., and Moritake,  K., 1980, “Stiffness and Elastic Behavior of Human Intracranial and Extracranial Arteries,” J. Biomech., 13, pp. 175–184.
Brossollet,  L. J., and Vito,  R. P., 1997, “The Effects of Cryopreservation on the Biaxial Mechanical Properties of Canine Saphenous Veins,” J. Biomech. Eng., 119, pp. 1–5.
Boock, R. J., and Thibault, L. E., 1990, “An Experimental and Analytical Approach to the Development of a Range of Neurovascular Trauma Indices,” 1990 International IRCOBI Conference on the Biomechanics of Impacts, pp. 169–180.
Thibault,  K. L., and Margulies,  S. S., 1998, “Age-Dependent Material Properties of the Porcine Cerebrum: Effect on Pediatric Inertial Head Injury Criteria,” J. Biomech., 31, pp. 1119–1126.

Figures

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Quasi-static and dynamic axial stress (first Piola-Kirchhoff)-stretch results for cortical arteries and veins
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Summary of mean toe-region and failure values for stress-stretch tests, by vessel type and testing rate. Toe-region curves were generated using A and B. Note that the lines connecting the yield and ultimate points are meaningless except to clarify which points are from the same group.
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Model-generated vessel load response, accompanied by its measured and simulated load cell force traces
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Comparison of stress-stretch behaviors from the current experiments with those reported in the literature for a variety of blood vessels. BV-bridging vein failure points for quasi-static and dynamic tests 11. MCA-subfailure major cerebral artery data 8. MCA II-failure data for major cerebral arteries 9. CCA, FemV, FemA, PopA-common carotid artery, femoral vein, femoral artery, popliteal artery 19.
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(a) Quasi-static and (b) dynamic image sequences for two arteries. Frame spacing is 0.4 seconds for (a) and 0.005 seconds for (b).
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Stress-stretch parameterization of example case. Toe and maximum modulus regions were fit using Eq. (2) and a line, respectively. Here, A=23.97,B=0.0036 MPa, and ModY=27.48 MPa.
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Dynamic model for load cell—grip—vessel system
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Photograph of sphere-beam impact dynamic testing setup
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Right temporal surface of brain during temporal lobectomy surgery. Arrow identifies suture used for in vivo length measurement. The dura has been pulled aside but the arachnoid remains intact.

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