TECHNICAL PAPERS: Fluids/Heat/Transport

A New Automated Method for the Quantification of Mitral Regurgitant Volume and Dynamic Regurgitant Orifice Area based on a Normalized Centerline Velocity Distribution using Color M-mode and Continuous Wave Doppler Imaging

[+] Author and Article Information
Dimitri Deserranno, Neil L. Greenberg, James D. Thomas, Mario J. Garcia

Cleveland Clinic Foundation, Department of Cardiology, Cardiovascular Imaging, 9500 Euclid Ave, Desk F15, Cleveland, OH 44195

J Biomech Eng 125(1), 62-69 (Feb 14, 2003) (8 pages) doi:10.1115/1.1531111 History: Received February 01, 2002; Revised September 01, 2002; Online February 14, 2003
Copyright © 2003 by ASME
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Error made by PISA in the estimation of regurgitant flow (Q) as a function of the radius r normalized by the orifice diameter d assuming the correct value of the radius r (solid line), 1 mm overestimation of the radius (gray line) and 1 mm underestimation of the radius (dashed line).
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Computational grid for a 5 mm orifice with a wall constraint of 180 degrees (1: mass flow inlet, 2: outflow, 3: pressure inlet, 4: symmetry axis, 5: orifice, I: proximal chamber, II: leaflet wall, III: distal chamber, α: wall constraint).
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(a) Velocity contour plot and (b) centerline velocity profile for regurgitation through a 5 mm diameter orifice with a 180 degrees constraint and a peak velocity of 3.04 m/s.
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Sample set of data (6 out of 132 profiles) obtained from the CFD model for α=100–240 degrees,d=2–9 mm,vp=3–8 m/sa) before and b) after normalization.
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Error in the estimated diameter by the NVD model for a misalignment in the Doppler scanline for α=120–220 degrees.
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(a) A typical color M-mode and (b) continuous wave Doppler image for an orifice diameter of 7.7 mm and peak pressure drop of 123 mmHg.
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Sample of the NVD model outputs for (a) the diameter and (b) the regurgitant flow rate by the Labview program for a 7.7 mm orifice (marked by gray line) with a regurgitant volume of 58.9 ml/beat and a peak pressure drop of 123 mmHg.
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(a) Estimated diameter and (b) regurgitant volume from the NVD model compared to the actual diameter of the phantom and the regurgitant volume by flow probe measurement.
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(a) Estimated regurgitant orifice area and (b) volume by the NVD model compared to the PISA method.




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