Injection of Highly Supersaturated Oxygen Solutions Without Nucleation

[+] Author and Article Information
J. Creech, V. Divino, W. Patterson, P. J. Zalesky

TherOx, Inc., 2400 Michelson Dr., Irvine, CA 92612

C. E. Brennen

California Institute of Technology, MC 104-44, Pasadena, CA 91125

J Biomech Eng 124(6), 676-683 (Dec 27, 2002) (8 pages) doi:10.1115/1.1519558 History: Received July 01, 2001; Revised June 01, 2002; Online December 27, 2002
Copyright © 2002 by ASME
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Grahic Jump Location
Frames from a normal video showing typical laminar (left) and turbulent jets (right) emerging from a 325 μm capillary
Grahic Jump Location
Six examples of high-speed video frames showing bubbles about to exit a particular 250 μm capillary. The distal end of the capillary is on the right.
Grahic Jump Location
Three examples of high-speed video frames showing the faint images of bubbles that have just emerged from a 325 μm capillary
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Typical histogram of the axial bubble length, s, divided by the tube diameter, d. Note that bubbles with s/d<1 are roughly spherical while those with s/d>1 are tube-filling slugs. This particular histogram is for a BKH-coated silica capillary with diameter 250 μm operating with a 3.45 MPa O2 solution at a velocity of 3.4 m/s.
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Chart showing the results of tests carried out to investigate nucleation caused by the onset of turbulent flow within the capillary. Horizontal lines show nucleating (solid lines) and non-nucleating (dashed lines) Reynolds number ranges for a number of different capillaries (with and without ethanolization) operated with various aqueous solutions of O2 and CO2 (saturation pressures shown). Onset of nucleation as the flow rate and Reynolds number was increased is shown by the two short vertical lines.
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Photographs of the distal ends of typical capillaries formed from silica (left) and PEEK (right)




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