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TECHNICAL PAPERS

Inertial Deposition Effects: A Study of Aerosol Mechanics in the Trachea Using Laser Doppler Velocimetry and Fluorescent Dye

[+] Author and Article Information
T. E. Corcoran

Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PAe-mail: corcorante@msx.upmc.edu

Norman Chigier

Mechanical Engineering Dept., Carnegie Mellon University, Pittsburgh, PAe-mail: chigier@andrew.cmu.edu

J Biomech Eng 124(6), 629-637 (Dec 27, 2002) (9 pages) doi:10.1115/1.1516572 History: Received November 01, 2000; Revised June 01, 2002; Online December 27, 2002
Copyright © 2002 by ASME
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References

Figures

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Steady flow experimental apparatus incorporating laryngeal and carinal castings from a female cadaver. Axial velocity contours, axial turbulence intensity contours and qualitative deposition measurements are made in the tracheal portion of the model.
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Axial velocity and turbulence intensity contours for Q=18.1LPM/Retrachea=1700 case in the Larynx/Trachea/Carina model. Dotted contours represent reverse flows. The contour interval for velocity is 0.5 m/s. The contour for axial turbulence intensity is 0.2 (dimensionless).
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Axial velocity and turbulence intensity contours for Q=41.1LPM/Retrachea=4000 case in the Larynx/Trachea/Carina model. Dotted contours represent reverse flows. The contour interval for velocity is 1.0 m/s for the positive axial flows and 0.5 m/s for the reverse flows. The contour interval for turbulence intensity is 0.2 (dimensionless).
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Velocity contours immediately downstream of the glottal constriction from two different models examined at Retrachea=1700. The first model is a cadaver-based cast model with a cast larynx and a round trachea. The next model uses the same cast larynx and round trachea, but includes also a casting of the carina. Note how this downstream element affects the upstream flows.
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Tracheal deposition depicted through the use of fluorescent dye. For each steady flow inhalation case a nebulizer was allowed to run to completion from 6 ml, 4 times. Images above depict the anterior side of the trachea which demonstrated high levels of deposition. Nebulizer operating conditions were identical for the three cases.
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Spray deposition variation for different sized sprays. The same total volume of dye was administered through the model in both cases.
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Deposition levels around the circumference of the upper trachea compared to velocity and turbulence intensity contours at the same location. Deposition levels are plotted radially in the middle frame. A deposition level of 10 is considered highest and 0 lowest.

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