Inertial Deposition Effects: A Study of Aerosol Mechanics in the Trachea Using Laser Doppler Velocimetry and Fluorescent Dye

[+] Author and Article Information
T. E. Corcoran

Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PAe-mail: corcorante@msx.upmc.edu

Norman Chigier

Mechanical Engineering Dept., Carnegie Mellon University, Pittsburgh, PAe-mail: chigier@andrew.cmu.edu

J Biomech Eng 124(6), 629-637 (Dec 27, 2002) (9 pages) doi:10.1115/1.1516572 History: Received November 01, 2000; Revised June 01, 2002; Online December 27, 2002
Copyright © 2002 by ASME
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Grahic Jump Location
Steady flow experimental apparatus incorporating laryngeal and carinal castings from a female cadaver. Axial velocity contours, axial turbulence intensity contours and qualitative deposition measurements are made in the tracheal portion of the model.
Grahic Jump Location
Axial velocity and turbulence intensity contours for Q=18.1LPM/Retrachea=1700 case in the Larynx/Trachea/Carina model. Dotted contours represent reverse flows. The contour interval for velocity is 0.5 m/s. The contour for axial turbulence intensity is 0.2 (dimensionless).
Grahic Jump Location
Axial velocity and turbulence intensity contours for Q=41.1LPM/Retrachea=4000 case in the Larynx/Trachea/Carina model. Dotted contours represent reverse flows. The contour interval for velocity is 1.0 m/s for the positive axial flows and 0.5 m/s for the reverse flows. The contour interval for turbulence intensity is 0.2 (dimensionless).
Grahic Jump Location
Velocity contours immediately downstream of the glottal constriction from two different models examined at Retrachea=1700. The first model is a cadaver-based cast model with a cast larynx and a round trachea. The next model uses the same cast larynx and round trachea, but includes also a casting of the carina. Note how this downstream element affects the upstream flows.
Grahic Jump Location
Tracheal deposition depicted through the use of fluorescent dye. For each steady flow inhalation case a nebulizer was allowed to run to completion from 6 ml, 4 times. Images above depict the anterior side of the trachea which demonstrated high levels of deposition. Nebulizer operating conditions were identical for the three cases.
Grahic Jump Location
Spray deposition variation for different sized sprays. The same total volume of dye was administered through the model in both cases.
Grahic Jump Location
Deposition levels around the circumference of the upper trachea compared to velocity and turbulence intensity contours at the same location. Deposition levels are plotted radially in the middle frame. A deposition level of 10 is considered highest and 0 lowest.




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