Noninvasive Measurement of Time-Varying Three-Dimensional Relative Pressure Fields Within the Human Heart

[+] Author and Article Information
T. Ebbers, L. Wigström

Department of Medicine and Care, Clinical Physiology and Department of Biomedical Engineering, Linköping University, SE-581 85 Linköping, Sweden

A. F. Bolger

Department of Medicine, University of California, San Francisco, CA

B. Wranne

Department of Medicine and Care, Clinical Physiology, Linköping University, SE-581 85 Linköping, Sweden

M. Karlsson

Department of Biomedical Engineering, Linköping University, SE-581 85 Linköping, Sweden

J Biomech Eng 124(3), 288-293 (May 21, 2002) (6 pages) doi:10.1115/1.1468866 History: Received August 16, 2001; Revised January 24, 2002; Online May 21, 2002
Copyright © 2002 by ASME
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Grahic Jump Location
Schematic drawing showing the orientation of the segmented three-dimensional volume containing the left atrium and ventricle during diastole
Grahic Jump Location
The computational domain Ω containing the segmented three-dimensional fluid volume ΩF with boundary ∂Ω
Grahic Jump Location
A long axis slice of the relative pressure field (color) and the velocity field (black streamlines) in the left side of the normal human heart at the onset, peak, and end of the early phase of diastolic inflow (a)–(c), the late phase of diastolic inflow (d)–(f ), and ventricular systole (g)–(i). 
Grahic Jump Location
The relative pressure field (gray scale) and the velocity field (black streamlines) around the mitral valve at the peak of the late phase of diastolic inflow. A single short axis slice of the three-dimensional data set is shown.
Grahic Jump Location
The velocity at the base and the pressure difference between the left atrium and apex (solid), the base and the apex (dashed), and the left ventricular outflow tract (LVOT) and the apex (dotted) over the cardiac cycle of the healthy volunteer. In the left panel, the localization of the manually placed points is shown in relation to a contour of the blood pool at mid-diastole (solid) and late systole (dotted).



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