A New Flow Chamber for the Study of Shear Stress and Transmural Pressure Upon Cells Adhering to a Porous Biomaterial

[+] Author and Article Information
Roxana Chotard-Ghodsnia, Agnès Drochon, Reinhard Grebe

UMR CNRS 6600 Biomécanique et Génie Biomédical, Université de Technologie de Compiègne, BP 20529, 60205 Compiègne cedex, France

J Biomech Eng 124(2), 258-261 (Mar 29, 2002) (4 pages) doi:10.1115/1.1448520 History: Received July 01, 2000; Revised May 01, 2001; Online March 29, 2002
Copyright © 2002 by ASME
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Grahic Jump Location
Top view of the opened flow chamber. The nylon screen (gray colored) is positioned on the bottom part and is surrounded by the bottom silicone ring. The porous biomaterial is then positioned on this nylon screen. To assemble, the upper part is turned over and fitted on the bottom part with screws.
Grahic Jump Location
Tangential mode flow system
Grahic Jump Location
(a) Filtrate flow rate, Qf, as a function of mean transmural pressure, TMPm, (b) Tangential flow rate Qout, as a function of the pressure drop in the chamber, ΔP




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