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TECHNICAL PAPERS

Microscopic Velocimetry With a Scaled-Up Model for Evaluating a Flow Field Over Cultured Endothelial Cells

[+] Author and Article Information
Shuichiro Fukushima, Takaaki Deguchi

Institute of Biomedical Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223-8522, Japan

Makoto Kaibara

Biopolymer Physics Laboratory, RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, 351-0106, Japan

Kotaro Oka, Kazuo Tanishita

Department of System Design Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama, 223-8522, Japan

J Biomech Eng 124(2), 176-179 (Mar 29, 2002) (4 pages) doi:10.1115/1.1449490 History: Received September 01, 2001; Revised October 01, 2001; Online March 29, 2002
Copyright © 2002 by ASME
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References

Figures

Grahic Jump Location
Surface geometry of a cell model scaled-up by a factor of 100. This model (16×16 mm) has 25 bulges corresponding to cells. The tracers were tracked at various heights on the measurement plane, every 0.1 mm vertical from the base (Z=−0.11,−0.01,0.09,0.19,0.29,0.39,0.49,1 mm). Here, zs is the surface geometry function, η (0.21 mm) is the amplitude of the surface oscillation, λx (4 mm) is the streamwise wavelength, and λy (4 mm) is the transverse wavelength.
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Velocity vectors in the measurement planes (4 subsections) near a center bulge. Highest point of the model surface is X=0,Y=0,Z=0.21 mm, and lowest point is X=0,Y=2,Z=−0.21 mm. Solid lines are the boundaries of the model surfaces at each section and the model surface is symmetrical along the X- and Y-axes (X=0,Y=0 mm).
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Normalized wall shear stress distribution on the scaled-up model. τ*zx*2zy*2zx*zxmacrozy*zymacro, where τmacro is the macroscopic wall shear stress (1.5 Pa); (a) analytical, (b) experimental.
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Wall shear stress distribution and height of the scaled-up model on the Y-axis (X=0 mm).

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