Dynamics of Human Coronary Arterial Motion and Its Potential Role in Coronary Atherogenesis

[+] Author and Article Information
Zhaohua Ding, Morton H. Friedman

Biomedical Engineering Center, The Ohio State University, Columbus, OH 43210-1002

J Biomech Eng 122(5), 488-492 (May 31, 2000) (5 pages) doi:10.1115/1.1289989 History: Received May 18, 1999; Revised May 31, 2000
Copyright © 2000 by ASME
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Illustration of the template matching process: (a) An initial template obtained from an image in the sequence to be processed. (b) Edge detection has been performed on another image in the sequence and the template is superimposed upon it. (c) The template has been iteratively deformed to match the edges of the vessel segment in the new image optimally. (d) A distorted grid indicates the deformation of the template, from which point-by-point correspondence between the two images of the vessel segment can be derived.
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Illustration of torsion. Curve segment C1 has no torsion as it lies entirely in a plane; curve segment C2 is a portion of a helix and therefore has constant torsion along its length.
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A reconstructed three-dimensional axis of a LAD segment. Motion trajectories covering two cardiac cycles are attached at selected locations. The length of the segment varies from 6.2 to 6.7 cm during the cardiac cycle.
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Pseudocolor plot of the variation of curvature with time and position along the vessel axis. The cardiac cycle is marked with arrows. The vessel segment analyzed in this figure is the same as in Fig. 3, with 0.5 cm excluded from each end. The axial points are Lagrangian markers approximately uniformly spaced along the vessel axis, about 0.3 mm apart.
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Coefficient of variation among individuals of the dynamic motion parameters of the right (RCA, n=4) and left anterior descending (LAD, n=8) coronary arteries
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Case mean coefficient of variation along the vessel axis of the dynamic motion parameters of the right (RCA, n=4) and left anterior descending (LAD, n=8) coronary arteries




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