Effect of Physiological Factors on Proximal Flow Convergence Upstream of an Incompetent Valve: An In-Vitro Study

[+] Author and Article Information
F. S. A. Guenet, A. P. Yoganathan

Cardiovascular Fluid Mechanics Laboratory, Institute for Bioengineering and Bioscience, School of Chemical Engineering, Georgia Institute of Technology, Atlanta, GA 30332-0100

P. G. Walker

Department of Mechanical Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom

M. W. Doyle, G. M. Pohost

Department of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL 35294

J Biomech Eng 119(1), 39-44 (Feb 01, 1997) (6 pages) doi:10.1115/1.2796062 History: Received November 18, 1994; Revised December 03, 1995; Online October 30, 2007


The flow (Q) through regurgitant valves may be quantified by multiplying the area of an isovelocity contour (isovel) by its velocity. This was tested computationally and experimentally (using MRI), Q = 14 to 141 ml/s, using flat and conical orifice plates. Plotting Q versus isovelocity radius, a plateau was found which, for low flow, corresponded to the true Q. At higher flow or large confinement, Q was overestimated. For conical plates, angle correction worked at low Q but not at higher values due to the formation of separation regions. These converted the cone plate into a flat plate. MRI produced similar results at 57 ml/s in that Q was correct with no angle correction. At low flow, MRI was too noisy to produce a clear plateau consistently.

Copyright © 1997 by The American Society of Mechanical Engineers
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