0
TECHNICAL PAPERS

A 3D-LDA Study of the Relation Between Wall Shear Stress and Intimal Thickness in a Human Aortic Bifurcation

[+] Author and Article Information
Kozaburo Hayashi

Department of Mechanical Engineering, Osaka University, Toyonaka, Osaka 560, Japan

Yutaka Yanai, Takeru Naiki

Section of Scientific Instrumentation and Control, Research Institute for Electronic Science, Hokkaido University, Sapporo 060, Japan

J Biomech Eng 118(3), 273-279 (Aug 01, 1996) (7 pages) doi:10.1115/1.2796007 History: Received October 19, 1994; Revised July 11, 1995; Online October 30, 2007

Abstract

A realistic model experiment on hemodynamics was performed to study correlations between wall shear stresses measured in a cast model of the aortic bifurcation and intimal thickness at each corresponding site of the native blood vessel from which the cast had been made. An elastic model of a 54 year old human aortic bifurcation was made of a polyurethane elastomer using a dipping method, and was perfused with Newtonian or non-Newtonian fluid under physiologic pulsatile flow condition. Local flow velocities were measured with an optical-fibered, 3-dimensional laser Doppler anemometer (3D-LDA) to determine wall shear stresses. Distribution of intimal thickness was determined using histological specimens of the native blood vessel. The results obtained are: 1) Non-Newtonian fluid rheology increased wall shear stresses; 2) Positive correlations were observed between intimal thickness and the maximum instantaneous wall shear stress, and 3) However, if we take only the data from the circumference at the level of the flow divider tip, there were negative correlations between them.

Copyright © 1996 by The American Society of Mechanical Engineers
Your Session has timed out. Please sign back in to continue.

References

Figures

Tables

Errata

Discussions

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related Journal Articles
Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In