Analysis of Thermal Injury Process Based on Enzyme Deactivation Mechanisms

[+] Author and Article Information
Yunsheng Xu

Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China

Renzhang Qian

Department of Power Engineering, Huazhong University of Science and Technology, Wuhan 430074, China

J Biomech Eng 117(4), 462-465 (Nov 01, 1995) (4 pages) doi:10.1115/1.2794208 History: Received March 19, 1993; Revised November 16, 1994; Online October 30, 2007


Based upon the analysis of enzyme-catalyzed reactions occurring in living tissue, a model of thermal injury process is presented in which the fraction of denatured enzyme protein was taken as the indicator of thermal damage degrees. The results from this model describe the dependence of thermal damage on exposure time and temperature elevation.

Copyright © 1995 by The American Society of Mechanical Engineers
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