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TECHNICAL BRIEFS

Microcirculation Impedance Analysis in Cat Lung

[+] Author and Article Information
Jian Gao, R. T. Yen

Department of Biomedical Engineering, The University of Memphis, Memphis, TN 38152

Wei Huang

Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093

J Biomech Eng 122(1), 99-103 (Aug 22, 1999) (5 pages) doi:10.1115/1.429647 History: Received November 24, 1998; Revised August 22, 1999
Copyright © 2000 by ASME
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References

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Fung,  Y. C., and Sobin,  S. S., 1972, “Pulmonary Alveolar Blood flow,” Circ. Res., 30, pp. 470–490.
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Lee, J. S., and Fung, Y. C., 1968, “Experiments on blood flow in alveoli models,” ASME Paper No. 68-WA/BHF-2.
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Yen, R. T., Zhang, F. Y., Fung, Y. C., and Zeng, Y. J., 1984, “Comparison of theory and experiments of blood flow in cat’s lung,” Biomechanics in China, Japan, and USA, Y. C. Fung et al., eds., Science, Beijing, China, pp. 240–253.
Yen, R. T., and Sobin, S. S., 1986, “Pulmonary blood flow in the cat: correlation between theory and experiment,” Frontiers in Biomechanics, G. W. Schmid-Schönbein et al., eds., Springer-Verlag, New York, pp. 365–376.
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Figures

Grahic Jump Location
Input impedance at entrance of capillary sheet of cat lungs when airway pressure (PA)=0 cm H2O, pleural pressure (PPl)=−10 cm H2O, pulmonary arterial pressure (Pa)=22 cm H2O, and flow rate=7 ml/s. The width of the cat’s pulmonary capillary sheet is estimated as 2.092×105 cm. Top: modulus per unit sheet width (per cm). Bottom: phase. Both are plotted against frequency. Zero-frequency input impedance modulus per unit width is 31.2×107 dyn-s/cm5.
Grahic Jump Location
Input impedance at exit of capillary sheet of cat lungs under the same conditions as in Fig. 1. Top: modulus per unit sheet width (per cm). Bottom: phase. Both are plotted against frequency. Zero-frequency input impedance modulus per unit width is 27.0×107 dyn-sec/cm5.
Grahic Jump Location
Comparison of input impedance at the pulmonary arterial trunk (upper: modulus; lower: phase) on three cases of morphometric variations. Case 1: physiological flow condition (nondimensional sheet thickness at arteriole h̃a=1.69 and venule h̃v=1.58, and main pulmonary artery diameter D0=0.986 cm). Case 2: a borderline zone 2 condition (h̃a=1.69,h̃v=1.0, and D0=0.986 cm). Case 3: a 20 percent decrease of D0 while h̃a=1.69,h̃v=1.58.
Grahic Jump Location
The effect of vascular elasticity on input impedance at the main pulmonary artery (upper: modulus; lower: phase) in three cases. Case 1: physiological flow condition (alveolar sheet compliance β*=0.219 μm/cm H2O, and main pulmonary arterial compliance β=3.30×10−4 Pa−1). Case 2: a 20 percent decrease of β*. Case 3: a 20 percent decrease of β.

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