An Analytical Study of Cryosurgery in the Lung

[+] Author and Article Information
J. C. Bischof, B. Rubinsky

Mechanical Engineering Department, University of California at Berkeley, Berkeley, CA 94720

J. Bastacky

Donner Laboratory, Lawrence Berkeley Laboratory, University of California at Berkeley, Berkeley, CA 94720

J Biomech Eng 114(4), 467-472 (Nov 01, 1992) (6 pages) doi:10.1115/1.2894096 History: Received June 01, 1991; Revised January 16, 1992; Online March 17, 2008


The process of freezing in healthy lung tissue and in tumors in the lung during cryosurgery was modeled using one-dimensional close form techniques and finite difference techniques to determine the temperature profiles and the propagation of the freezing interface in the tissue. A thermal phenomenon was observed during freezing of lung tumors embedded in healthy tissue, (a) the freezing interface suddenly accelerates at the transition between the tumor and the healthy lung, (b) the frozen tumor temperature drops to low values once the freezing interface moves into the healthy lung, and (c) the outer boundary temperature has a point of sharp inflection corresponding to the time at which the tumor is completely frozen.

Copyright © 1992 by The American Society of Mechanical Engineers
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