Flow Measurements in a Highly Curved Atherosclerotic Coronary Artery Cast of Man

[+] Author and Article Information
L. H. Back

Jet propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109

T. K. Liem

University of Southern California School of Medicine, Los Angeles, CA 90033

E. Y. Kwack

Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109

D. W. Crawford

Department of Medicine, Cardiology Division, University of Southern California, Los Angeles, CA 90033

J Biomech Eng 114(2), 232-240 (May 01, 1992) (9 pages) doi:10.1115/1.2891377 History: Received December 10, 1990; Revised October 10, 1991; Online March 17, 2008


Flow visualization and wall pressure measurements were made in a polyurethane cast of a cadaver coronary artery with a significant ā€œsā€ shaped reverse curvature. A sucrose solution was used to simulate the kinematic viscosity of blood, with flow rates in the physiologic range. Flow visualization demonstrated significant secondary flow patterns in the wall vicinity, which increased with increasing Reynolds number. Random dye dispersion was observed at a Reynolds number of about 400, but not at 200. Dye filament patterns in the transition between the first and second curved region were predominantly influenced by the second curved region at lower Reynolds numbers, and by the first curved region at higher Re. Local wall pressure measurements demonstrated a significant centrifugal effect with large radial pressure differences across the casting. Flow resistances for the casting were considerably greater than reference Poiseuille flow values, and increased further with pulsatile flow.

Copyright Ā© 1992 by The American Society of Mechanical Engineers
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