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RESEARCH PAPERS

In-Vivo Indentation of Human Skin

[+] Author and Article Information
Y. Lanir

Department of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa, 3200 Israel

S. Dikstein, A. Hartzshtark, V. Manny

School of Pharmocology, Hebrew University, Jerusalem, 91120 Israel

J Biomech Eng 112(1), 63-69 (Feb 01, 1990) (7 pages) doi:10.1115/1.2891127 History: Received September 22, 1988; Revised July 24, 1989; Online March 17, 2008

Abstract

Indentation tests were carried out on the forehead skin of volunteers under loading pressures of 0–5 KPa. The indentation was found to increase asymptomatically with loading pressure. In an attempt to develop a quantitative index for aging of the skin, its response to indentation loading was analyzed in reference to its glycosaminoglycan (GAG) containing ground substance and fibers’ network microstructure. An analytic model that considers the skin as an incompressible solid-fluid mixture was developed and utilized to simulate the skin’s indentation response. Following parameter fitting, the predicted results are in close agreement with the data. The model can thus serve as a tool for evaluating the effect of changes in the dermis components which accompany aging.

Copyright © 1990 by The American Society of Mechanical Engineers
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