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RESEARCH PAPERS

Effect of Mild Atherosclerosis on Flow Resistance in a Coronary Artery Casting of Man

[+] Author and Article Information
L. H. Back, Y. I. Cho, R. F. Cuffel

Jet Propulsion Laboratory, California Institute of Technology, Pasadena, Calif. 91109

D. W. Crawford

Department of Medicine, Cardiology Division, University of Southern California, Los Angeles, Calif. 90033

J Biomech Eng 106(1), 48-53 (Feb 01, 1984) (6 pages) doi:10.1115/1.3138456 History: Received March 01, 1983; Revised August 31, 1983; Online June 15, 2009

Abstract

An in-vitro flow study was conducted in a mildly atherosclerotic main coronary artery casting of man using sugar-water solutions simulating blood viscosity. Steady flow results indicated substantial increases in pressure drop, and thus flow resistance at the same Reynolds number, above those for Poiseuille flow by 30 to 100 percent in the physiological Reynolds number range from about 100 to 400. Time-averaged pulsatile flow data showed additional 5 percent increases in flow resistance above the steady flow results. Both pulsatile and steady flow data from the casting were found to be nearly equal to those from a straight, axisymmetric model of the casting up to a Reynolds number of about 200, above which the flow resistance of the casting became gradually larger than the corresponding values from the axisymmetric model.

Copyright © 1984 by ASME
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