Models of Cell Interaction Based on Differential Adhesion

[+] Author and Article Information
S. Childress

Courant Institute of Mathematical Sciences, New York University, New York, N.Y. 10014

J Biomech Eng 106(1), 36-41 (Feb 01, 1984) (6 pages) doi:10.1115/1.3138454 History: Received April 10, 1983; Revised October 19, 1983; Online June 15, 2009


Recent efforts to model the mechanical interaction of aggregates of biological cells are reviewed. Differential adhesion is discussed as a means of creating a field of stress equivalent to tension elements at interfaces between unlike cell types. Several numerical algorithms are described and applied to shortening and folding of cell sheets, three-dimensional monolayers, and two-dimensional cell aggregates.

Copyright © 1984 by ASME
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